1013910-75-2Relevant academic research and scientific papers
Intramolecular acid-base catalysis of a phosphate diester: Modeling the ribonuclease mechanism
Orth, Elisa S.,Brandao, Tiago A. S.,Milagre, Humberto M. S.,Eberlin, Marcos N.,Nome, Faruk
, p. 2436 - 2437 (2008)
The hydrolysis of the phosphate diester bis(2-(1-methyl-1H-imidazolyl)phenyl) phosphate BMIPP was evaluated as an intramolecular model for the ribonuclease A mechanism. Kinetic and thermodynamic data, isotope effects and ESI-MS and ESI-MS/MS analysis supp
Intramolecular catalysis of phosphodiester hydrolysis by two imidazoles
Orth, Elisa S.,Brandao, Tiago A.S.,Souza, Bruno S.,Pliego, Josefredo R.,Vaz, Boniek G.,Eberlin, Marcos N.,Kirby, Anthony J.,Nome, Faruk
, p. 8513 - 8523 (2010)
Two imidazole groups act together to catalyze the hydrolysis of the phosphodiester bis(2-(1-methyl-1H-imidazolyl)phenyl) phosphate (BMIPP). A full investigation involving searching computational and electrospray ionization (ESI-MS-/MS) and ultra mass spec
