1014702-75-0

Upstream product

• 616888-34-7 C₁₇H₂₃NO₃ 
• 86732-22-1 2-benzyloctahydropyrrolo[3,4-c]pyrrole 
• 140-29-4 phenylacetonitrile 
• 92248-94-7 3-cyano-3-phenyl-glutaric acid dimethyl ester 
• 1014702-72-7 C₁₃H₁₅NO₃ 
• 52423-63-9 2-(3-phenyl-5-yl-pyrrolidin-3-yl)-ethanol 
• 192940-81-1 1-(t-butoxycarbonyl)-3-phenyl-3-(2-hydroxyethyl)pyrrolidine 

Downstream Products

• 1014702-76-1 C₂₃H₃₅N₃O₂ 
• 1014701-47-3 {5-[2-(1-cyclopenanecarbonyl-3-phenyl-pyrrolidin-1-yl)-ethyl]-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl}-[3,5-dimethyl-1-(5-trifluoromethyl-pyridin-2-yl)-1H-pyrazol-4-yl]-methanone 
• 1014702-79-4 C₃₅H₄₃F₃N₆O₃ 
• 1014702-45-4 (5-{2-[1-(3,3-difluoro-cyclobutanecarbonyl)-3-phenyl-pyrrolidin-3-yl]-ethyl}-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-(3,5-dimethyl-1-pyrimidin-5-yl-1H-pyrazol-4-yl)-methanone 
• 1014701-42-8 5-(5-{2-[1-(3,3-difluoro-cyclobutanecarbonyl)-3-phenyl-pyrrolidin-3-yl]-ethyl}-hexahydro-pyrrolo[3,4-c]pyrrole-2-carbonyl)-4,6-dimethyl-pyridine-2-carbonitrile 
• 1014703-06-0 C₃₃H₄₃N₇O₃ 
• 1014702-77-2 C₃₂H₄₁N₅O₃ 
• 1014703-42-4 C₂₈H₃₅N₇O 

Relevant academic research and scientific papers

OCTAHYDROPYRROLO [3, 4-C] PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS

Chemokine receptor antagonists, in particular, 3,7-diazabicyclo [3.3.0] octane compounds according to formula (I) wherein R1-R3 and Ar are as defined herein are antagonists of chemokine CCR5 receptors which are useful for treating or preventing an human immunodeficiency virus (HIV) infection, or treating AIDS or ARC. The invention further provides methods for treating diseases that are alleviated with CCR5 antagonists. The invention includes pharmaceutical compositions and methods of using the compounds for the treatment of these diseases. The invention further includes processes for the preparation of compounds according to formula (I).