616888-34-7

Basic information

• Product Name: tert-Butyl 3-(2-oxoethyl)-3-phenylpyrrolidine-1-carboxylate
• Synonyms: tert-Butyl 3-(2-oxoethyl)-3-phenylpyrrolidine-1-carboxylate
• CAS NO: 616888-34-7
• Molecular Formula: C₁₇H₂₃NO₃
• Molecular Weight: 289.36942
• Mol File: 616888-34-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: tert-Butyl 3-(2-oxoethyl)-3-phenylpyrrolidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl 3-(2-oxoethyl)-3-phenylpyrrolidine-1-carboxylate(616888-34-7)
• EPA Substance Registry System: tert-Butyl 3-(2-oxoethyl)-3-phenylpyrrolidine-1-carboxylate(616888-34-7)

Safety Data

• Hazardous Substances Data: 616888-34-7(Hazardous Substances Data)

Upstream product

• 192940-81-1 1-(t-butoxycarbonyl)-3-phenyl-3-(2-hydroxyethyl)pyrrolidine 
• 140-29-4 phenylacetonitrile 
• 92248-94-7 3-cyano-3-phenyl-glutaric acid dimethyl ester 
• 1014702-72-7 C₁₃H₁₅NO₃ 
• 52423-63-9 2-(3-phenyl-5-yl-pyrrolidin-3-yl)-ethanol 

Downstream Products

• 1014702-75-0 C₃₀H₄₁N₃O₂ 
• 1014702-73-8 C₃₀H₄₁N₅O₃ 
• 1014702-76-1 C₂₃H₃₅N₃O₂ 
• 1014703-42-4 C₂₈H₃₅N₇O 
• 1014702-77-2 C₃₂H₄₁N₅O₃ 
• 1014703-06-0 C₃₃H₄₃N₇O₃ 
• 1014701-42-8 5-(5-{2-[1-(3,3-difluoro-cyclobutanecarbonyl)-3-phenyl-pyrrolidin-3-yl]-ethyl}-hexahydro-pyrrolo[3,4-c]pyrrole-2-carbonyl)-4,6-dimethyl-pyridine-2-carbonitrile 
• 1014702-45-4 (5-{2-[1-(3,3-difluoro-cyclobutanecarbonyl)-3-phenyl-pyrrolidin-3-yl]-ethyl}-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-(3,5-dimethyl-1-pyrimidin-5-yl-1H-pyrazol-4-yl)-methanone 
• 1014702-79-4 C₃₅H₄₃F₃N₆O₃ 
• 1014701-47-3 {5-[2-(1-cyclopenanecarbonyl-3-phenyl-pyrrolidin-1-yl)-ethyl]-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl}-[3,5-dimethyl-1-(5-trifluoromethyl-pyridin-2-yl)-1H-pyrazol-4-yl]-methanone 

Relevant articles and documents

Evaluation of secondary amide replacements in a series of CCR5 antagonists as a means to increase intrinsic membrane permeability. Part 1: Optimization of gem-disubstituted azacycles

Replacement of a secondary amide with an N-acyl or N-sulfonyl gem-disubstituted azacyle in a series of CCR5 antagonists led to the identification of compounds with excellent in vitro HIV antiviral activity and increased intrinsic membrane permeability.