101478-65-3

Upstream product

• 623-00-7 4-bromobenzenecarbonitrile 
• 1239384-20-3 3-(1,3-dioxolan-2-yl)prop-1-yl[2-(2-hydroxyprop-2-yl)phenyl]diisopropylsilane 
• 18742-02-4 2-bromo-2-(2-ethyl)dioxolane 
• 104-85-8 para-methylbenzonitrile 

Downstream Products

• 101478-66-4 4-(4-oxobutyl)benzonitrile 
• 186350-77-6 4-(6-methylhept-5-en-2-yl)benzonitrile 
• 186350-82-3 4-(1-methyl-4-oxobutyl)benzonitrile 
• 186350-79-8 4-[4-(1,3-dioxolan-2-yl)but-2-yl]benzonitrile 

Relevant academic research and scientific papers

Cross-coupling reactions through the intramolecular activation of Alkyl(triorgano)silanes

(Figure Presented) Cross-Si-ing the Jordan: Cross-coupling reactions of 2-(2-hydroxyprop-2-yl)phenylsubstituted alkylsilanes with a variety of aryl halides proceed in the presence of palladium and copper catalysts. The use of K3PO4 base allows for highly chemoselective alkyl coupling with both primary and secondary alkyl groups (Alk).

Synthesis of rac-ar-curcumen-15-al

Starting from p-tolunitrile (4) via alkylation with the bromo-acetal 12 (→ 8), and with MeI (→ 9), hydrolysis to 10, Wittig reaction (→ 7) and DIBAH reduction, the rac-ar-curcumen-15-al (2) was obtained. The cumin-like, citrus odor of rac-2 is similar to that of the isolated (-)-2. VCH Verlagsgesellschaft mbH, 1997.

Liquid crystals

Compounds of the formula STR1 wherein n stands for the number 0 or 1; the rings A1, A2 and A3 represent 1,4-phenylene, 2-fluoro-1,4-phenylene or trans-1,4-cyclohexylene or one of these rings also represents a 2,5-disubstituted pyrimidine ring or a trans-2,5-disubstituted m-dioxane ring; X1 represents a single covalent bond, --COO--, --OOC--, --CH2 CH2 --, p--C6 H4 --, --CH2 CH2 --p-- C6 H4 --, --CH2 CH2 --p--C6 H4 --CH2 CH2 -- or, insofar as the rings A1 and A2 represent 1,4-phenylene, also --NON--; R2 represents 1E-alkenyl, 2Z-alkenyl, 3E-alkenyl, 4-alkenyl or alkenyloxy, with the proviso that the oxygen atom in alkenyloxy is linked with a saturated carbon atom; and R1 signifies 1E-alkenyl, 2Z-alkenyl, 3E-alkenyl, 4-alkenyl or, insofar as R2 represents alkenyloxy, also alkyl, their manufacture, as well as liquid crystalline mixtures and the use for electro-optical purposes.

Novel liquid crystal mixtures

Liquid crystalline mixtures containing compounds of the formula STR1 wherein n stands for the number 0 or 1; X1 and X2 denote single covalent bonds or one of the symbols X1 and X2 also denotes --COO--, --OOC-- or --CH2 CH2 --; the rings A1, A2 and A3 represent 1,4-phenylene, 2-fluoro-1,4-phenylene or trans-1,4-cyclohexylene or one of these rings also represents a 2,5-disubstituted pyrimidine ring or a trans-2,5-disubstituted m-dioxane ring; R1 signifies 4-alkenyl or on a cyclohexyl ring also 2Z-alkenyl; and R2 denotes alkyl, alkoxy, --CN or --NCS, as well as the manufacture of these compounds and the use for electro-optical purposes are described.