1015445-58-5

Basic information

• Product Name: {4-[4-(4-fluorophenyl)-3-(2-methoxyethyl)-2-methylsulfanyl-1H-imidazol-5-yl]pyridin-2-yl}-(tetrahydropyran-4-yl)amine
• Synonyms: {4-[4-(4-fluorophenyl)-3-(2-methoxyethyl)-2-methylsulfanyl-1H-imidazol-5-yl]pyridin-2-yl}-(tetrahydropyran-4-yl)amine
• CAS NO: 1015445-58-5
• Molecular Weight: 442.557
• Mol File: 1015445-58-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: {4-[4-(4-fluorophenyl)-3-(2-methoxyethyl)-2-methylsulfanyl-1H-imidazol-5-yl]pyridin-2-yl}-(tetrahydropyran-4-yl)amine(CAS DataBase Reference)
• NIST Chemistry Reference: {4-[4-(4-fluorophenyl)-3-(2-methoxyethyl)-2-methylsulfanyl-1H-imidazol-5-yl]pyridin-2-yl}-(tetrahydropyran-4-yl)amine(1015445-58-5)
• EPA Substance Registry System: {4-[4-(4-fluorophenyl)-3-(2-methoxyethyl)-2-methylsulfanyl-1H-imidazol-5-yl]pyridin-2-yl}-(tetrahydropyran-4-yl)amine(1015445-58-5)

Safety Data

• Hazardous Substances Data: 1015445-58-5(Hazardous Substances Data)

Upstream product

• 38041-19-9 4-aminotetrahydropyran 
• 908381-35-1 2-fluoro-4-[4-(4-fluorophenyl)-1-(2-methoxyethyl)-2-(methylsulfanyl)-1H-imidazol-5-yl]pyridine 

Relevant articles and documents

Design, synthesis, and biological evaluation of novel tri- and tetrasubstituted imidazoles as highly potent and specific ATP-mimetic inhibitors of p38 MAP kinase: Focus on optimized interactions with the enzyme's surface-exposed front region

The synthesis, biological testing, and SAR of novel 2,4,5- and 1,2,4,5-substituted 2-thioimidazoles are described. Amino, oxy, or thioxy substituents at the 2-position of the pyridinyl moiety were evaluated for their contributions to inhibitor potency and