908381-35-1

Upstream product

• 908382-45-6 4-(4-fluorophenyl)-5-(2-fluoro-4-pyridyl)-1-(2-methoxyethyl)-1,3-dihydro-2H-imidazole-2-thione 
• 74-88-4 methyl iodide 
• 556-64-9 methyl thiocyanate 
• 1015514-21-2 1-(4-fluorophenyl)-2-(2-fluoro-4-pyridyl)-2-[(2-methoxyethyl)amino]ethanone 
• 908381-46-4 4-[5-(4-fluorophenyl)-3-(2-methoxyethyl)-2-methylsulfanyl-3H-imidazol-4-yl]pyridin-2-ylamine 

Downstream Products

• 908382-38-7 {4-[4-(4-fluorophenyl)-3-(2-methoxyethyl)-2-methylsulfanyl-1H-imidazol-5-yl]pyridin-2-yl}-phenylamine 
• 908382-39-8 {4-[5-(4-fluorophenyl)-3-(2-methoxyethyl)-2-methylsulfanyl-3H-imidazol-4-yl]-pyridin-2-yl}-(4-methoxyphenyl)-amine 
• 908382-41-2 2-Fluoro-4-[5-(4-fluorophenyl)-2-methanesulfinyl-3-(2-methoxyethyl)-3H-imidazol-4-yl]-pyridine 
• 1015445-58-5 {4-[4-(4-fluorophenyl)-3-(2-methoxyethyl)-2-methylsulfanyl-1H-imidazol-5-yl]pyridin-2-yl}-(tetrahydropyran-4-yl)amine 
• 1009308-64-8 (S)-2-{4-[4-(4-fluorophenyl)-3-(2-methoxyethyl)-2-methylsulfanyl-1H-imidazol-5-yl]pyridin-2-ylamino}-propan-1-ol 
• 1009308-63-7 (R)-2-{4-[4-(4-fluorophenyl)-3-(2-methoxyethyl)-2-methylsulfanyl-1H-imidazol-5-yl]pyridin-2-ylamino}-propan-1-ol 
• 1009308-40-0 C₂₅H₃₁FN₄O₂S 
• 1015445-55-2 {4-[4-(4-fluorophenyl)-3-(2-methoxyethyl)-2-methylsulfanyl-1H-imidazol-5-yl]pyridin-2-yl}-((S)-1-phenylethyl)amine 
• 908381-51-1 {4-[4-(4-fluorophenyl)-3-(2-methoxyethyl)-2-methylsulfanyl-1H-imidazol-5-yl]pyridin-2-yl}-((R)-1-phenylethyl)amine 
• 1015445-57-4 ((R)-1-cyclohexylethyl)-{4-[4-(4-fluorophenyl)-3-(2-methoxyethyl)-2-methylsulfanyl-1H-imidazol-5-yl]pyridin-2-yl}amine 
• 908382-22-9 cyclohexyl-{4-[4-(4-fluorophenyl)-3-(2-methoxyethyl)-2-methylsulfanyl-1H-imidazol-5-yl]pyridin-2-yl}amine 
• 1041850-97-8 (R)-2-{4-[4-(4-fluorophenyl)-3-(2-methoxyethyl)-2-methylsulfanyl-1H-imidazol-5-yl]pyridin-2-ylamino}cyclohexanol 
• 1009308-22-8 4-[5-(4-Fluoro-phenyl)-3-(2-methoxy-ethyl)-2-methylsulfanyl-3H-imidazol-4-yl]-2-(1-phenyl-ethoxy)-pyridine 
• 1009308-72-8 4-[5-(4-Fluoro-phenyl)-2-methanesulfonyl-3-(2-methoxy-ethyl)-3H-imidazol-4-yl]-2-isopropoxy-pyridine 

Relevant academic research and scientific papers

Regiospecific and highly flexible synthesis of 1,4,5-trisubstituted 2-sulfanylimidazoles from structurally diverse ethanone precursors

Imidazoles represent important bioactive scaffolds in medicinal chemistry. More than 2,500 structures are listed in drug discovery databases and over 3,000 patents have been claimed for imidazole-based structures. Recent imidazole pharmacophores have targ

Imidazole compounds having an antiinflammatory effect

The invention relates to 2-sulfinyl- or 2-sulfonyl-substituted imidazole derivatives of the formula I in which the radicals R1, R2, R3 and R4 have the meaning indicated in the description. The compounds of the i

2-SULFINYL- AND 2-SULFONYL-SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR USE AS CYTOKINE INHIBITORS

The invention relates to 2-sulfinyl- or 2-sulfonyl-substituted imidazole derivatives of the formula (I) in which the radicals R1, R2, R3 and R4 have the meaning indicated in the description. The compounds of the