101581-06-0

Usage

Uses

Used in Pharmaceutical Industry:
1,3-Dibromo-2-methyl-5-nitrobenzene serves as a key intermediate in the synthesis of various pharmaceuticals. It is utilized for its ability to be chemically modified to produce a spectrum of medicinally relevant compounds, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 1,3-Dibromo-2-methyl-5-nitrobenzene is employed in the production of pesticides and other crop protection agents. Its chemical properties make it a valuable component in the creation of effective and targeted agrochemicals.
Used as a Building Block in Organic Synthesis:
Beyond its direct applications, 1,3-Dibromo-2-methyl-5-nitrobenzene is an important building block in the chemical industry, used in the synthesis of a wide array of organic compounds for various purposes. Its structural features facilitate its integration into complex organic molecules, making it a useful precursor in multiple chemical reactions.
It is crucial to handle 1,3-Dibromo-2-methyl-5-nitrobenzene with caution due to its toxic and potentially harmful properties, ensuring safety measures are in place throughout its use in research and industrial applications.

Upstream product

• 99-99-0 1-methyl-4-nitrobenzene 
• 90914-81-1 4-bromo-3-methylacetanilide 
• 827-32-7 4-bromo-5-methyl-2-nitrophenylamine 
• 7745-93-9 2-bromo-4-nitrotoluene 

Downstream Products

• 444664-09-9 1-Bromomethyl-2,6-dibromo-4-nitrobenzene 
• 21900-48-1 3-bromo-2-methylbenzoic acid chloride 
• 943722-20-1 [(3-bromo-2-methylphenyl)methyl]amine hydrochloride 
• 919363-09-0 3-bromo-2-methylbenzamide 
• 76006-33-2 3-bromo-2-methylbenzoic acid 
• 1177558-44-9 (3,5-dibromo-4-methylphenyl)amine hydrochloride 
• 392318-87-5 2,6-dibromo-3,5-dinitro-toluene 
• 444661-91-0 5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-(piperidin-4-ylamino)-3,4-dihydroquinazolin-2(1H)-one 
• 444665-68-3 5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-3-(4-methoxybenzyl)-7-nitro-3,4-dihydroquinazolin-2(1H)-one 
• 444665-70-7 7-amino-5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-3-(4-methoxybenzyl)-3.4-dihydroquinazolin-2(1H)-one 
• 444665-66-1 N-(2,6-dibromo-4-nitrobenzyl)-N'-(2.6-dichlorophenyl)-N-(4-methoxybenzyl)urea 

Relevant academic research and scientific papers

Through space interaction between ferrocenes mediated by a thioether

A series of conformationally constrained 2,6-bisferrocenylphenyl thioethers were synthesized via Suzuki-Miyaura cross coupling reactions. Structural information was obtained using X-ray crystallography and dynamic 1H NMR spectroscopic studies,

BORON-CONTAINING SMALL MOLECULES

Compounds, pharmaceutical formulations, and methods of treating bacterial infections are disclosed.

Efficient synthesis of rigid ladder polymers via palladium catalyzed annulation

We report a new method to synthesize rigid ladder polymers using efficient palladium catalyzed annulation reactions with low catalyst loading (1 mol %). Rigid ladder polymers with benzocyclobutene backbone linkages can be synthesized from copolymerization of readily accessible aryl dibromides and norbornadiene or polymerization of AB type monomers bearing norbornene and aryl bromide or triflate moieties. High molecular weight (10-40 kDa) rigid ladder polymers can be obtained with complete monomer conversions. Diverse monomers also gave different, fixed ladder polymer conformations. The ladder polymers exhibited excellent thermal stability, high carbonization yield, and large intrinsic porosity.

Dual Pharmacophores - PDE4-Muscarinic Antagonistics

The present invention is directed to novel compounds of Formula (I) and pharmaceutically acceptable salts thereof, pharmaceutical compositions and their use as dual chromaphores having inhibitory activity against PDE4 and muscarinic acetylcholine receptors (mAChRs), and thus being useful for treating respiratory diseases.

Dual Pharmacophores - PDE4-Muscarinic Antagonistics

The present invention relates to novel compounds of Formula (I) and their use in the treatment of respiratory diseases, including anti-inflammatory and allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, rhinitis (e.g. allergic rhinitis), atopic dermatitis or psoriasis.

Dual Pharmacophores - PDE4-Muscarinic Antagonistics

The present invention is directed to novel compounds of Formula (I), pharmaceutical compositions and their use in therapy, for example as inhibitors of phosphodiesterase type IV (PDE4) and as antagonists of muscarinic acetylcholine receptors (mAChRs), in the treatment of/and or prophylaxis of respiratory diseases, including antiinflammatory and/or allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, rhinitis (e.g. allergic rhinitis), atopic dermatitis or psoriasis.

DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS

The present invention is directed to novel compounds of Formula's (I) - (VI), and pharmaceutically acceptable salts thereof, pharmaceutical compositions and their use in therapy, for example as inhibitors of phosphodiesterase type IV (PDE4) and as antagonists of muscarinic acetylcholine receptors (mAChRs), in the treatment of and/or prophylaxis of respiratory diseases, including inflammatory and/or allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, rhinitis (e.g. allergic rhinitis), atopic dermatitis or psoriasis.

Poly(thiaheterohelicene): A stiff conjugated helical polymer comprised of fused benzothiophene rings

(Chemical Equation Presented) A novel helical aromatic polymer comprised of fused benzothiophene rings, poly(thiaheterohelicene), was synthesized via an intramolecular ring-closing reaction with a controlled helicity to one-sided bias. The synthetic helic