10163-41-4 Usage
Uses
Used in Pharmaceutical Research:
N-(3-chlorophenyl)but-2-enamide is used as an intermediate in pharmaceutical research for the development of new drugs. Its unique chemical structure and potential biological activities make it a promising candidate for the synthesis of various pharmaceutical compounds.
Used in Organic Synthesis:
N-(3-chlorophenyl)but-2-enamide is used as an intermediate in organic synthesis for the preparation of various organic compounds. Its reactivity and functional groups allow for the formation of a wide range of chemical products.
Used in Drug Discovery:
N-(3-chlorophenyl)but-2-enamide is used in drug discovery for the identification and development of new therapeutic agents. Its potential biological activities, such as anti-inflammatory and analgesic properties, make it a valuable compound for the exploration of novel drug targets and treatments.
Used in the Development of Anti-inflammatory Agents:
N-(3-chlorophenyl)but-2-enamide is used as a starting material in the development of anti-inflammatory agents. Its potential to modulate inflammatory pathways and alleviate inflammation-related symptoms makes it a promising candidate for the creation of new anti-inflammatory drugs.
Used in the Development of Analgesic Agents:
N-(3-chlorophenyl)but-2-enamide is used in the development of analgesic agents to alleviate pain and discomfort. Its potential analgesic properties make it a valuable compound for the synthesis of new pain-relieving medications.
Check Digit Verification of cas no
The CAS Registry Mumber 10163-41-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,1,6 and 3 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 10163-41:
(7*1)+(6*0)+(5*1)+(4*6)+(3*3)+(2*4)+(1*1)=54
54 % 10 = 4
So 10163-41-4 is a valid CAS Registry Number.
10163-41-4Relevant academic research and scientific papers
Tin for Organic Synthesis, 11. A Mild and Effective Synthesis of α,β-unsaturated Carboxamides and Sulfonamides by Electrophilic Substitution of Alkenylstannanes with Isocyanates
Niestroj, Michael,Neumann, Wilhelm P.,Thies, Olaf
, p. 1131 - 1136 (2007/10/02)
A new and effective method for the preparation of a variety of olefinic carboxamides 6a-k and N-(4-methylphenylsulfonyl)carboxamides 7a-d is described.The reaction of aryl and alkyl isocyanates 4a-c or 4-methylphenylsulfonyl isocyanate 5 with 1-alkenyltrialkylstannanes 1a-e and di-1-alkenyldibutylstannanes 2a-c in the presence of aluminium trichloride provides the corresponding N-aryl-substituted olefinic carboxamides 6a-k or the N-(4-methylphenylsulfonyl)-substituted olefinic carboxamides 7a-d in good yields.The stannyl moiety is superior to hydrogen as a leaving group and enables electrophilic ipso substitution at the vinylic system.In the case of di-1-alkenyldibutylstannanes the substitutions are also stereospecific, whereas the reactions of 1-alkenyltrialkylstannanes with isocyanates proceed with partial isomerisation. - Key Words: Electrophilic vinylic substitution / Isocyanates / α,β-Unsaturated amides, synthesis of / Carbodestannylation / Alkenylstannanes, applications of
