1016538-33-2

Basic information

• Product Name: 2-(1-(p-tolyl)ethyl)cyclopentan-1-one
• Synonyms: 2-(1-(p-tolyl)ethyl)cyclopentan-1-one
• CAS NO: 1016538-33-2
• Molecular Weight: 202.296
• Mol File: 1016538-33-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(1-(p-tolyl)ethyl)cyclopentan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-(p-tolyl)ethyl)cyclopentan-1-one(1016538-33-2)
• EPA Substance Registry System: 2-(1-(p-tolyl)ethyl)cyclopentan-1-one(1016538-33-2)

Safety Data

• Hazardous Substances Data: 1016538-33-2(Hazardous Substances Data)

Upstream product

• 86561-30-0 1-(4-methylphenyl)ethyl acetate 
• 19980-43-9 1-(trimethylsilyloxy)cyclopentene 

Relevant articles and documents

Branched-selective intermolecular ketone α-alkylation with unactivated alkenes via an enamide directing strategy

We describe a strategy for intermolecular branched-selective α-alkylation of ketones using simple alkenes as the alkylating agents. Enamides derived from isoindolin-1-one provide an excellent directing template for catalytic activation of ketone α-positions. High branched selectivity is obtained for both aliphatic and aromatic alkenes using a cationic iridium catalyst. Preliminary mechanistic study favors an Ir-C migratory insertion pathway.