1016557-35-9

Upstream product

• 7776-34-3 L-proline hydrochloride 
• 313644-41-6 C₂₁H₂₂N₆O₈ 
• 1016557-32-6 C₂₃H₂₆N₆O₈ 
• 909797-74-6 C₂₃H₃₀N₂O₈ 
• 145325-45-7 1',5'-bis[2-methoxy-4-(methoxycarbonyl)-5-nitrophenoxy]pentane 
• 147-85-3 L-proline 

Downstream Products

• 1016557-39-3 C₃₅H₄₆N₁₀O₁₀ 
• 313644-47-2 C₃₁H₃₆N₈O₈ 
• 313644-43-8 C₃₃H₄₀N₈O₁₀ 

Relevant academic research and scientific papers

A facile intramolecular azido/amido reductive cyclization approach: synthesis of pyrrolobenzodiazepines and their dimers

A new synthetic pathway has been developed for the preparation of imine-containing pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) and their dimers. Selective reduction of aromatic azides as well as aliphatic amides in a single step leading to an intramolecular

Synthesis of pyrrolo[2,1-c][1,4]benzodiazepines via reductive cyclization of ω-Azido carbonyl compounds by TMSI: An efficient preparation of antibiotic DC-81 and its dimers

ω-Azido carbonyl compounds on reaction with trimethylsilyl iodide (in situ prepared from TMSCI/NaI) led to the formation of diazepine imines in good yields under mild conditions. This methodology has been applied to the parent unsubstituted pyrrolobenzodiazepine, the natural product DC-81 and its dimers. (C) 2000 Elsevier Science Ltd.