101664-59-9

Basic information

• Product Name: 2-CHLORO-3,4-DIMETHOXYPYRIDINE HYDROCHLORIDE
• Synonyms: 2-CHLORO-3,4-DIMETHOXYPYRIDINE HYDROCHLORIDE;2-Chlor-3,4-dimethoxypyridine;2-Chloro-3,4-dimethoxypyridine
• CAS NO: 101664-59-9
• Molecular Formula: C₇H₈ClNO₂
• Molecular Weight: 173.6
• Mol File: 101664-59-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 37-42℃
• Boiling Point: 241.5 °C at 760 mmHg
• Flash Point: 99.9 °C
• Appearance: /
• Density: 1.217 g/cm³
• Vapor Pressure: 0.0554mmHg at 25°C
• Refractive Index: 1.509
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 2-CHLORO-3,4-DIMETHOXYPYRIDINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-3,4-DIMETHOXYPYRIDINE HYDROCHLORIDE(101664-59-9)
• EPA Substance Registry System: 2-CHLORO-3,4-DIMETHOXYPYRIDINE HYDROCHLORIDE(101664-59-9)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• RIDADR: UN 2811 6.1 / PGIII
• HazardClass: IRRITANT
• Hazardous Substances Data: 101664-59-9(Hazardous Substances Data)

Usage

Uses

2-Chloro-3,4-dimethoxypyridine is used in the preparation of 3, 4-dimethoxy-pyridine by using nickel(II) chloride hexahydrate and triphenylphosphine as a catalyst.

InChI:InChI=1/C7H8ClNO2/c1-10-5-3-4-9-7(8)6(5)11-2/h3-4H,1-2H3

Upstream product

• 67-56-1 methanol 
• 101664-56-6 2-Chlor-3-fluor-4-nitropyridin-1-oxid 
• 109613-93-6 3,4-dimethoxypyridine 
• 6298-19-7 2-chloro-3-aminopyridine 
• 462-08-8 pyridin-3-ylamine 
• 85386-94-3 2-Chlor-3-fluorpyridin-1-oxid 
• 17282-04-1 2-chloro-3-fluoropyridine 
• 101664-58-8 2-Chlor-3,4-dimethoxypyridin-1-oxid 
• 109613-91-4 2-chloro-3-methoxy-4-nitropyridine 

Downstream Products

• 72016-31-0 orelline 
• 37338-80-0 3,3',4,4'-tetrahydroxy-2,2'-bipyridine-1,1'-dioxide 
• 1204295-69-1 2-chloropyridine-3,4-diol 
• 101664-55-5 3,3',4,4'-tetramethoxy-2,2'-bipyridine 
• 109613-93-6 3,4-dimethoxypyridine 

Relevant articles and documents

First synthesis of 4-chloro-2,2-difluoro[1,3]dioxole[4,5-c]pyridine

The 2,2-difluorobenzodioxole moiety has been introduced in medicinal chemistry research as a potential metabolically more stable derivative of the benzodioxole fragment. Herein we present, to the best of our knowledge, the first synthesis of 4-chloro-2,2-

Syntheses of Hydroxylated Bipyridines, I. - Orellanine, the Poison of a Toadstool

Two syntheses of orellanine, -3,3',4,4'-tetrol-1,1'-dioxide (5b), are developed which comprise 10 or 11 steps, respectively.The chemical reactions of 5b with diazomethane and on UV irradiation are described.