10171-38-7

Basic information

• Product Name: ethoxymethanol
• Synonyms: ethoxymethanol
• CAS NO: 10171-38-7
• Molecular Formula: C₃H₈O₂
• Molecular Weight: 76.09442
• EINECS: 233-446-1
• Mol File: 10171-38-7.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 101.7°Cat760mmHg
• Flash Point: 43.3°C
• Appearance: /
• Density: 0.928g/cm³
• Vapor Pressure: 19.5mmHg at 25°C
• Refractive Index: 1.385
• PKA: 13.28±0.10(Predicted)
• CAS DataBase Reference: ethoxymethanol(CAS DataBase Reference)
• NIST Chemistry Reference: ethoxymethanol(10171-38-7)
• EPA Substance Registry System: ethoxymethanol(10171-38-7)

Safety Data

• Hazardous Substances Data: 10171-38-7(Hazardous Substances Data)

Usage

Description

Ethoxymethanol, with the chemical formula C3H8O2, is an organic solvent that is widely used in various industrial applications. It is a flammable liquid with a mild, pleasant odor and is commonly used as a cleaning agent, in chemical reactions, and as a solvent for different substances. Ethoxymethanol is also utilized in the production of dyes, resins, and other organic compounds. However, it is crucial to handle this chemical with care due to its potential harmful effects if inhaled, swallowed, or in contact with the skin, as well as its adverse environmental impacts if not properly disposed of.

Uses

Used in Cleaning Agents:
Ethoxymethanol is used as a cleaning agent for its ability to dissolve various substances, making it effective in removing dirt, grease, and other contaminants.
Used in Chemical Reactions:
As a versatile solvent, ethoxymethanol is employed in numerous chemical reactions to facilitate processes and improve the efficiency of the reactions.
Used in Solvent Applications:
Ethoxymethanol is used as a solvent for various substances, allowing for the dissolution and mixing of different compounds in various industrial processes.
Used in Dye Production:
Ethoxymethanol is utilized in the production of dyes, where it serves as a solvent or a reactant in the synthesis of colorants.
Used in Resin Production:
In the manufacturing of resins, ethoxymethanol plays a crucial role as a solvent or a component in the reaction process, contributing to the formation of the final product.
Used in Other Organic Compounds Production:
Ethoxymethanol is also employed in the production of other organic compounds, where it acts as a solvent or a reactant, depending on the specific application and synthesis process.

InChI:InChI=1/C3H8O2/c1-2-5-3-4/h4H,2-3H2,1H3

Upstream product

• 64-17-5 ethanol 
• 124-38-9 carbon dioxide 
• 50-00-0 formaldehyd 

Downstream Products

• 2621-78-5 ethyl N-benzylcarbamate 
• 62873-16-9 5-methyl-3-(methylidene)dihydrofuran-2(5H)-one 
• 50-00-0 formaldehyd 
• 64-17-5 ethanol 
• 52452-08-1 4-Ethoxymethoxy-2-oxo-6-p-tolyl-cyclohex-3-enecarboxylic acid ethyl ester 

Relevant articles and documents

Secondary α-Deuterium Isotope Effects for the Cleavage of Formaldehyde Hemiacetals through Concerted and Specific-Base-Catalyzed Pathways

The observed secondary α-deuterium isotope effects for catalysis by acetate ion of the cleavage of formaldehyde hemiacetals increase from k2H/k2D = 1.23 to 1.28 to 1.34 with decreasing pK of the leaving alcohol in the series ethanol, chloroethanol, and trifluoroethanol.The pH-independent reaction shows a smaller isotope effect of 1.15-1.14 for the ethyl and chloroethyl hemiacetals.These reactions involve general-base catalysis of alcohol attack in the addition direction and the kinetically equivalent cleavage of the hemiacetal anion with general-acid catalysis by acetic acid or the proton in the cleavage direction.The results indicate that the amount of C-O cleavage in the transition state increases with decreasing pK of the alcohol and increasing pK of the acid catalyst, corresponding to a negative coefficient pyy'=δρn/-δpK1g = δβ1g/-δ? and a positive coefficient pxy = δρn/-δpKHA = δα/δ?.These results provide additional support for a concerted reaction mechanism with an important role of proton transfer in the transition state.Qualitative and semiquantitative characterizations of the transition state are presented in terms of reaction coordinate diagrams that are defined by the structure-reactivity parameters.The properties of the transition state suggest that the reaction is best regarded as an electrophilic displacement on the oxygen atom by the proton and by the carbonyl group in the cleavage and addition directions, respectively.The large secondary isotope effect of k2H/k2D = 1.63 for cleavage of the chloroethyl and trifluoroethyl hemiacetals catalyzed by hydroxide ion indicates a late transition state for alkoxide expulsion from the hemiacetal anion.

Ruthenium-Catalyzed Synthesis of Dialkoxymethane Ethers Utilizing Carbon Dioxide and Molecular Hydrogen

The synthesis of dimethoxymethane (DMM) by a multistep reaction of methanol with carbon dioxide and molecular hydrogen is reported. Using the molecular catalyst [Ru(triphos)(tmm)] in combination with the Lewis acid Al(OTf)3resulted in a versatile catalytic system for the synthesis of various dialkoxymethane ethers. This new catalytic reaction provides the first synthetic example for the selective conversion of carbon dioxide and hydrogen into a formaldehyde oxidation level, thus opening access to new molecular structures using this important C1source.

SIDEROPHORE CONJUGATED PYRAZOLIDINONES, AND ANALOGUES THEREOF

In one aspect, the invention provides compounds and methods that are useful for treating bacterial infections.

Process for the production of y-methyl-a-methylene-y-butyrolactone from reaction of levulinic acid and hydrogen with recycle of unreacted levulinic acid followed by reaction of crude y-valerolactone and formaldehyde, both reactions being carried out in the supercritical or near-critical fluid phase

Process for the production of γ-methyl-α-methylene-γ-butyrolactone from reaction of levulinic acid and hydrogen with recycle of unreacted levulinic acid and reaction of crude γ-valerolactone and formaldehyde, both reactions being carried out in the supercritical or near-critical fluid phase.