10172-70-0

Upstream product

• 1076-38-6 4-hydroxy[1]benzopyran-2-one 
• 555-16-8 4-nitrobenzaldehdye 
• 6093-68-1 6-hydroxycoumarin 
• 1334232-92-6 1-((4-nitrophenyl)(pyrrolidin-1-yl)methyl)naphthalen-2-ol 
• 619-73-8 4-nitrobenzyl chloride 
• 22105-09-5 4‐hydroxycoumarin 

Downstream Products

• 13475-38-2 7-(4-nitrophenyl)-7H-bis-[1]benzopyrano[4,3-b:3',4'-c]pyran-6,8-dione 

Relevant academic research and scientific papers

Highly efficient synthesis of dicoumarols and xanthene derivatives in presence of Br?nsted–Lewis acidic ionic liquids catalyst

A series of metal chloride-based acidic ionic liquids have been prepared and used as an efficient catalyst in one-pot multicomponent synthesis of biscoumarins and substituted xanthenes derivatives under solvent-free conditions. Among the acidic ionic liqu

A novel synthesis of biscoumarin derivatives catalyzed by ZnCl2under solvent-free coditions

Zinc chloride (ZnCl2) is used as an efficient catalyst condensation of 4-hydroxycoumarin and with various aromatic aldehydes leading to the formation of biscoumarin derivatives. Easy isolation of the products, short reaction times, excellent yi

Synthesis, in vitro evaluation and molecular docking studies of biscoumarin thiourea as a new inhibitor of α-glucosidases

Biscoumarin analogs 1-18 have been synthesized, characterized by EI-MS and 1H NMR and evaluated for α-glucosidase inhibitory potential. All compounds showed variety of α-glucosidase inhibitory potential ranging in between 13.5 ± 0.39 and 104.62

Mohr's salt hexahydrate: A novel, cheap and powerful reagent for green synthesis of biscoumarins on water

Anew and convenient method for the synthesis of biscoumarins based on the condensation of 4-hydroxycoumarin and aromatic aldehydes in the presence of Mohr's salt hexahydrate (ferrous ammonium sulfate hexahydrate) as a novel catalyst on water is developed.

Crystal structure and activities of three biscoumarin derivatives against Staphylococcus aureus

Three new biscoumarin derivatives, namely, 3,3′-[(4-nitrophenyl)methylene]bis(4-hydroxy-2H-chromen-2-one) (NBH), 3,3′-[(4-methoxyphenyl)methylene]bis(4-hydroxy-2H-chromen-2-one) (MBH) and 3,3′-[(4-chloromethylphenyl)methylene]bis(4-hydroxy-2H-chromen-2-on

Synthesis of biscoumarin derivatives using poly(4-vinylpyridine)-supported dual acidic ionic liquid as a heterogeneous catalyst

A supported dual acidic ionic liquid catalyst was easily prepared from its starting materials (namely poly(4-vinylpyridine) and 1,4-butanesultone) and used as a highly efficient heterogeneous catalytic system for the synthesis of biscoumarin derivatives f

Dicoumarol derivatives: Green synthesis and molecular modelling studies of their anti-LOX activity

Dicoumarol derivatives were synthesized in the InCl3 catalyzed pseudo three-component reactions of 4-hydroxycoumarin with aromatic aldehydes in excellent yields. The reactions were performed in water under microwave irradiation. All synthesized

Efficient one-pot synthesis of bis(4-hydroxycoumarin)methanes in the presence of sulfonic acid functionalized nanoporous silica (SBA-Pr-SO 3H)

An efficient and simple method for the synthesis of bis(4-hydroxycoumarin) methanes has been achieved through a one-pot condensation of aryl aldehydes and 4-hydroxycoumarin in the presence of nanoporous solid acid catalyst of SBA-Pr-SO3H with pore size of

Carbon-SO3H: An efficient catalyst for the synthesis of biscoumarin under ambient reaction conditions and their in silico studies

In this article, we have established a highly promising approach for the synthesis of biscoumarins via domino Knoevenagel–Michael condensation of 4-hydroxycoumarin and aromatic aldehydes in 2:1 ratio using carbon-SO3H as a solid acid catalyst i

Novel SO3H-functionalized ionic liquids based on benzimidazolium cation: Efficient and recyclable catalysts for one-pot synthesis of biscoumarin derivatives

In this article, a new group of SO3H-functionalized ionic liquids based on benzimidazolium cation was synthesized and used as environmentally benign catalysts for the one-pot synthesis of biscoumarin derivatives. The ionic liquids showed high catalytic activities and reusabilities with good to excellent yields of the desired products. H 0 (Hammett function) values and the minimum-energy geometries of SO3H-functionalized ionic liquids were determined and the results revealed that the acidities and catalytic activities of ionic liquids in the synthesis of biscoumarin derivatives were related to their structures. Graphical Abstract: The simple, more efficient way for synthesis of biscoumarin derivatives has been developed. This new method abandon the traditional hazardous organic liquid and is carried out by using a one-pot reaction of 4-hydroxycoumarin with aromatic aldehydes in the presence of novel SO 3H-functionalized ionic liquids based on benzimidazolium cation as catalysts. The ionic liquids showed high catalytic activities and reusabilities with good to excellent yields of the desired products. H 0 (Hammett function) values and the minimum-energy geometries of SO3H- functionalized ionic liquids were determined and the results revealed that the acidities and catalytic activities of ionic liquids in the synthesis of biscoumarin derivatives were influenced by their structures.[Figure not available: see fulltext.]