101758-68-3

Basic information

• Product Name: (R)-(+)-5-triphenylmethyloxymethyl-2 (5H)-furanone
• Synonyms: (R)-(+)-5-triphenylmethyloxymethyl-2 (5H)-furanone
• CAS NO: 101758-68-3
• Molecular Weight: 356.421
• Mol File: 101758-68-3.mol

Chemical Properties

• CAS DataBase Reference: (R)-(+)-5-triphenylmethyloxymethyl-2 (5H)-furanone(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-5-triphenylmethyloxymethyl-2 (5H)-furanone(101758-68-3)
• EPA Substance Registry System: (R)-(+)-5-triphenylmethyloxymethyl-2 (5H)-furanone(101758-68-3)

Safety Data

• Hazardous Substances Data: 101758-68-3(Hazardous Substances Data)

Upstream product

• 112837-17-9 (R)-(+)-5-(hydroxymethyl)furan-2(5H)-one 
• 76-83-5 trityl chloride 

Downstream Products

• 132489-32-8 (S)-4-((3aS,4R,6aR)-5-Benzyl-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrol-4-yl)-4-benzyloxy-butan-1-ol 
• 132489-31-7 (3aS,4R,6aR)-5-Benzyl-4-((S)-1-benzyloxy-but-3-enyl)-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole 
• 132430-67-2 2,3-O-Isopropylidene-1,4-di-O-methanesulfonyl-5-O-trityl-D-ribitol 
• 84709-46-6 2,3-O-isopropylidene-5-O-(triphenylmethyl)-D-ribitol 
• 132430-78-5 (2S,3S,4R)-N-benzyl-2-formyl-3,4-(isopropylidenedioxy)pyrrolidine 
• 117736-94-4 (2R,3S,4R)-3,4-dibenzyloxy-2-(methoxymethoxy)methyl-N-benzylpyrrolidine 
• 117719-26-3 (2R,3S,4R)-3,4-dihydroxy-2-(methoxymethoxy)methyl-N-benzylpyrrolidine 
• 113626-63-4 (1S,2R,8R,8aR)-4-Benzyl-1,2,8-tris-benzyloxy-octahydro-indolizinium; chloride 
• 113200-95-6 (1S,2R,8S,8aR)-4-Benzyl-1,2,8-tris-benzyloxy-octahydro-indolizinium; chloride 
• 113626-62-3 (2R,3S,4R)-N-benzyl-2-<(1R)-1-benzyloxy-4-hydroxybutanyl>-3,4-bis(benzyloxy)pyrrolidine 
• 132561-49-0 (S)-4-((2R,3S,4R)-1-Benzyl-3,4-bis-benzyloxy-pyrrolidin-2-yl)-4-benzyloxy-butan-1-ol 
• 113626-59-8 (2R,3S,4R)-N-benzyl-2-<(1R)-1-benzyloxy-3-butenyl>-3,4-bis(benzyloxy)pyrrolidine 
• 132561-50-3 (2R,3S,4R)-1-Benzyl-3,4-bis-benzyloxy-2-((S)-1-benzyloxy-but-3-enyl)-pyrrolidine 
• 132430-77-4 (R)-4-((3aS,4R,6aR)-5-Benzyl-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrol-4-yl)-4-benzyloxy-butan-1-ol 

Relevant articles and documents

Total synthesis of progesterone receptor ligands, (-)-PF1092A, B and C

Microbial metabolites (-)-PF1092A, B and C belonging to an eremophilane sesquiterpene group are synthesized from (R)-5-hydroxymethyl-2(5H)-furanone through the SnCl4 promoted cyclization of an α-keto methyl sulfone and dimethyl acetal followed by a Stork annulation which gives the octalone core.

Tetrahydronaphthofuranone derivatives and process for producing the same

Compounds represented by the following formula (I) and pharmaceutically acceptable salts thereof are disclosed. The compounds have progesterone receptor binding inhibitory activity and, hence, can be used as therapeutic and prophylactic agents for progest