10177-32-9 Usage
General Description
Methyl 4-methoxynicotinate is a chemical compound with the molecular formula C8H9NO3. It is a derivative of nicotinic acid, a compound known for its various biological activities. Methyl 4-methoxynicotinate is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various pharmaceuticals. It is also known for its vasodilatory and anti-inflammatory properties, which make it a potential candidate for the treatment of cardiovascular diseases and inflammatory conditions. Additionally, it has been reported to possess antioxidant and neuroprotective effects, making it a compound of interest in the field of medicinal chemistry and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 10177-32-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,1,7 and 7 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 10177-32:
(7*1)+(6*0)+(5*1)+(4*7)+(3*7)+(2*3)+(1*2)=69
69 % 10 = 9
So 10177-32-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NO3/c1-11-7-3-4-9-5-6(7)8(10)12-2/h3-5H,1-2H3
10177-32-9Relevant articles and documents
The Reaction of N -Trimethylsilyl-Substituted Heteroarylamines with Esters and Thioesters: An Efficient Protocol to Access Diheteroarylamides
Koperniku, Ana,Zamiri, Maryam,Grierson, David S.
, p. 1779 - 1790 (2019)
The S -benzyl thioester and methyl ester derivatives of a representative 4-pyridinone-based carboxylic acid were sufficiently activated to react efficiently in amide coupling reactions with the amide anion generated in situ from the N -trimethylsilyl derivative of different weakly nucleophilic heteroarylamines. In acetonitrile as solvent, the precipitated diheteroarylamide products were isolated in pure form by vacuum filtration. This simple amide bond forming protocol can be readily adapted to the parallel synthesis of compound libraries.