10180-76-4

Upstream product

• 2225-79-8 11βH,13-dihydrocostunolide 

Downstream Products

• 39012-15-2 Isoacolamon 
• 140169-48-8 6α-O-acetyl-p-coumaroyloxy-5,7αH-eudesm-3-ene 
• 140169-47-7 6α-O-acetyl-p-coumaroyloxy-5,7αH-eudesm-4(15)-ene 
• 140384-72-1 6-epi-β-verbesinol coumarate 
• 140224-91-5 6-epi-α-verbesinol p-coumarate 
• 472-07-1 junenol 
• 85354-58-1 2-((1R,6S)-2,6-Dimethyl-6-{3-[2-(4-methyl-pent-3-enyl)-[1,3]dithian-2-yl]-propyl}-cyclohex-2-enylmethoxy)-tetrahydro-pyran 
• 112358-84-6 Toluene-4-sulfonic acid 3-((1R,2R)-2-hydroxymethyl-1,3-dimethyl-cyclohex-3-enyl)-propyl ester 
• 85354-59-2 1-((1S,2R)-2-Hydroxymethyl-1,3-dimethyl-cyclohex-3-enyl)-8-methyl-non-7-en-4-one 
• 85440-75-1 [(1R,6S)-2,6-Dimethyl-6-(8-methyl-4-methylene-non-7-enyl)-cyclohex-2-enyl]-methanol 
• 85354-57-0 2-[(1R,6R)-6-(3-Iodo-propyl)-2,6-dimethyl-cyclohex-2-enylmethoxy]-tetrahydro-pyran 
• 85354-56-9 [(1R,6R)-6-(3-Iodo-propyl)-2,6-dimethyl-cyclohex-2-enyl]-methanol 
• 85354-55-8 3-((1R,2R)-2-Hydroxymethyl-1,3-dimethyl-cyclohex-3-enyl)-propan-1-ol 
• 85329-65-3 2-[(1R,6S)-6-(3-[1,3]Dithian-2-yl-propyl)-2,6-dimethyl-cyclohex-2-enylmethoxy]-tetrahydro-pyran 

Relevant academic research and scientific papers

Palladium II promoted rearrangement of germacranolides. Synthesis of (+)-stoebenolide and (+)-dehydromelitensin

Catalytic amounts of bis(benzonitrile)palladium (II) chloride enhanced reaction rates of germacranolides Cope rearrangement to elemanolides. On the other hand, equimolecular amounts of the palladium complex transformed germacranolides into eudesmanolides. These phenomena provide a versatile procedure for the synthesis of eudesmanolides and elemanolides under relatively mild experimental conditions. Thus, (+)-stoebenolide and (+)-dehydromelitensin were alternatively synthesized starting out from (+)-salonitenolide.