472-07-1

Usage

Uses

Used in Pharmaceutical Industry:
(1S,8aβ)-Decahydro-2α-isopropyl-4aβ-methyl-8-methylenenaphthalen-1β-ol is used as a potential active pharmaceutical ingredient for its possible biological activities. Given its unique molecular structure and the presence of various functional groups, it may interact with biological targets in ways that could be harnessed for medicinal purposes.
Used in Organic Synthesis:
In the field of organic synthesis, (1S,8aβ)-Decahydro-2α-isopropyl-4aβ-methyl-8-methylenenaphthalen-1β-ol can be utilized as a building block or intermediate in the creation of more complex organic molecules. Its specific structural features may allow for the development of novel compounds with tailored properties.
Used in Medicinal Research:
(1S,8aβ)-Decahydro-2α-isopropyl-4aβ-methyl-8-methylenenaphthalen-1β-ol is used as a subject of study in medicinal research to explore its potential therapeutic effects. (1S,8aβ)-Decahydro-2α-isopropyl-4aβ-methyl-8-methylenenaphthalen-1β-ol's unique features may provide insights into new mechanisms of action or reveal its ability to treat specific conditions, pending further investigation.

InChI:InChI=1/C15H26O/c1-10(2)12-7-9-15(4)8-5-6-11(3)13(15)14(12)16/h10,12-14,16H,3,5-9H2,1-2,4H3/t12-,13+,14-,15+/m0/s1

Upstream product

• 20674-02-6 6α-hydroxygermacra-1(10),4-diene 
• 10180-80-0 isojunenol 
• 140169-49-9 3α-(O-methanesulfonyl)-5,7αH,4,6,11βH-eudesman-6,12-olide 
• 10180-76-4 (3S,3aS,5aR,9aR,9bS)-3,5a,9-Trimethyl-3a,4,5,5a,6,7,9a,9b-octahydro-3H-naphtho[1,2-b]furan-2-one 
• 13902-54-0 (3S,3aS,5aS,9S,9aR,9bS)-3,5a,9-trimethyloctahydronaphtho[1,2-b]furan-2,8-dione 
• 553-21-9 costunolide 
• 16887-26-6 1,1,4a-Trimethyl-Δ⁸-octalin 
• 1203-04-9 perhydro-4a,8,8-trimethylnaphthalen-1α-ol 
• 56194-27-5 methyl (6E)-farnesoate 
• 95421-16-2 (SR,RS)-monocyclofarnesol 
• 95421-18-4 (SR,RS)-monocyclofarnesal 
• 23986-74-5 germacrene D 
• 35932-59-3 Voleneolmonoacetat 
• 121711-38-4 torilensulfat 

Downstream Products

• 140169-47-7 6α-O-acetyl-p-coumaroyloxy-5,7αH-eudesm-4(15)-ene 
• 140384-72-1 6-epi-β-verbesinol coumarate 

Relevant academic research and scientific papers

A shorter route to the synthesis of (+)-junenol isojunenol, and their coumarate esters from (-)-santonin

This paper reports on the chemical conversion of (-)-santonin into (+)-junenol, isojunenol and their coumarate esters. The identity of (+)-junenol and 8-epi-β-verbesinol is also established.

Sulfuric Acid-Catalyzed Cyclization of Germacrene-D to Eudesmane-4,6-diol Cyclic Sulfate

Reaction of germacrene-D with sulfuric acid afforded a eudesmane-4,6-diol cyclic sulfate (1).The structure of 1 was determined by spectral analysis and chemical correlations.

Synthetic Studies of Terpenoids. Part 7. Synthetic Studies leading to the Total Synthesis of Eudesmane Sesquiterpenoids

The synthesis of two naturally occuring sesquiterpenes, (+/-)-junenol (1) and (+/-)-acolamone (2), from the bicyclic ketone (3) is described.The introduction of an isopropyl chain at C-7 of the bicyclic ketone was attempted by three different procedures and yielded ketone (5) which, on reduction with sodium and ethanol, gave the alcohol (12).This, on oxidation with lead tetra-acetate and iodine in cyclohexane, yielded the cyclic ether (13) and regenerated the ketone (5).Oxidation of compound (13) with chromium(VI) oxide in acetic acid afforded the keto-acid (15) which, on oxidative decarboxylation with lead tetra-acetate, furnished acolamone which was reduced with sodium borohydride in ethanol to (+/-)-junenol.