1018239-17-2

Upstream product

• 120-72-9 indole 
• 22568-07-6 1-chloro-2-(2-nitrovinyl)benzene 
• 22568-07-6 1-chloro-2-[(E)-2-nitrovinyl]benzene 

Relevant academic research and scientific papers

Synthesis of 2-Indolyl-1-nitroalkane derivatives using nanocrystalline titanium(iv) oxide

The catalytic Friedel-Crafts alkylation of indoles with nitroalkenes to furnish 2-indolyl-1-nitroalkane derivatives at room temperature with moderate to excellent yields is reported using nanocrystalline titanium(IV) oxide (nano-TiO2) catalyst. In all cas

Electrostatically enhanced phosphoric acids and their applications in asymmetric friedel-crafts alkylations

A series of electrostatically enhanced phosphoric acid catalysts were synthesized and studied. These compounds possess two positively charged N-octylpyridinium or triarylphosphonium ion centers at the 3,3′-positions of the (R)-BINOL backbone to enhance re

Baker's yeast as an efficient biocatalyst for regioselective 1,4-conjugate addition of indoles to nitroolefins in aqueous medium

The 1,4-conjugate addition of indoles to nitroolefins was efficiently carried out in aqueous media using baker's yeast as a biocatalyst at room temperature. The merits of the present method are operational simplicity, easy workup, utilization of an inexpensive catalyst, free from hazardous organic solvents and good yields of products. The generality of this method was demonstrated by synthesizing an array of diverse 3-substituted indole derivatives and could be extended for dialkylation of 1,4-bis-(2-nitrovinyl)benzene.

An efficient class of bis-NHC salts: Applications in Pd-catalyzed reactions under mild reaction conditions

This study describes an efficient class of bis-N-heterocyclic carbene (bis-NHC) salts that can be easily made from commercially available and inexpensive starting materials. The application of these salts to Pd-catalyzed reactions is described. The palladium (Pd) catalyst generated in situ was highly effective under mild reaction conditions.

Preparation of a chiral Pt12 tetrahedral cage and its use in catalytic Michael addition reaction

The reaction of chiral cis-[(1S,2S)-dch]Pt(NO3)2 (M) [where (1S,2S)-dch = (1S,2S)-1,2-diaminocyclohexane] with a hexadentate ligand (L) in 3:1 stoichiometric ratio yielded a [12+4] self-assembled chiral M12L4 mo

1,1-Diamino-2-nitroethylenes as excellent hydrogen bond donor organocatalysts in the Michael addition of carbon-based nucleophiles to β-nitrostyrenes

A new class of hydrogen bond donor catalysts based on the 1,1-diamino-2-nitroethylene scaffold has been introduced for the activation of trans-β-nitrostyrenes toward reactions with a range of carbon-based nucleophiles, affording the corresponding adducts

An efficient and clean Michael addition of indoles to electron-deficient olefins under solvent- and catalyst-free condition

An efficient Michael addition of indoles to electron-deficient olefins under solvent- and catalyst-free condition afforded biologically important 3-substituted indole derivatives in good to excellent yields was reported. The acidic N-H proton of indole pl

Simple and efficient Friedel-Crafts alkylation of 1H-indole with electron-deficient alkenes promoted by zinc acetate

An efficient method for the Friedel-Crafts alkylation of 1H-indole with nitro alkenes in the presence of zinc acetate is described. The procedure is applicable to a variety of nitro alkenes and substituted indoles, and the yields are very high.