22568-07-6

Basic information

• Product Name: Benzene, 1-chloro-2-(2-nitroethenyl)-, (E)-
• Synonyms: 2-chloronitrostyrene
• CAS NO: 22568-07-6
• Molecular Formula: C8H6ClNO2
• Molecular Weight: 183.594
• Mol File: 22568-07-6.mol
• Article Data: 77

Chemical Properties

• CAS DataBase Reference: Benzene, 1-chloro-2-(2-nitroethenyl)-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-chloro-2-(2-nitroethenyl)-, (E)-(22568-07-6)
• EPA Substance Registry System: Benzene, 1-chloro-2-(2-nitroethenyl)-, (E)-(22568-07-6)

Safety Data

• Hazardous Substances Data: 22568-07-6(Hazardous Substances Data)

Usage

General Description

Benzene, 1-chloro-2-(2-nitroethenyl)-, (E)- is a chemical compound that is also known by the chemical name 2-chloro-1-(2-nitroethenyl)benzene. It is a colorless to light yellow liquid that is used primarily as an intermediate in the production of pesticides. The E isomer of this compound is the more stable and predominant form. It is considered to be a harmful chemical, with potential health effects including irritation of the eyes, skin, and respiratory tract, as well as potential carcinogenic properties. Due to its hazardous nature, it is important to handle and use this compound with proper safety precautions.

Upstream product

• 85536-83-0 1-(2-chloro-phenyl)-2-nitro-ethanol 
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Downstream Products

• 15851-93-1 2-chloro-5,β-dinitro-styrene 
• 147089-80-3 (Z)-1-(2-bromo-2-nitrovinyl)-2-chlorobenzene 
• 10125-44-7 2-Chlor-1-<1,3,3,3-tetranitro-propyl-2>-benzol 
• 10125-43-6 2-Chlor-1-<1,3,3-trinitro-butyl-2>-benzol 
• 950592-86-6 C₁₀H₁₀ClNO 
• 950839-92-6 (E)-5-(2-chlorophenyl)-6-nitro-1-(trimethylsilyl)-2-hexen-1-one 
• 60610-77-7 methyl 2-carbomethoxy-4-nitro-3-(2-chloro-phenyl)-butyrate 
• 1003879-49-9 (2-nitro-1-(2-chlorophenyl)ethyl)di-1-naphthyl phosphine oxide 

Relevant articles and documents

A robust heterogeneous Co-MOF catalyst in azide-alkyne cycloaddition and Friedel-Crafts reactions as well as hydrosilylation of alkynes

Organic reactions using metal-organic frameworks (MOFs) as catalysts are promising with regard to their environmentally friendly features and potential catalyst recyclability. A robust Co(ii)-MOF {[Co2(l-mac)(4,4-bpt)(H2O)]·3.5H2O}n (1) and its enantiomer {[Co2(d-mac)(4,4-bpt)(H2O)]·3.5H2O}n (2) (l/d-mac = basic forms of l/d-malic acid, 4,4-Hbpt = 3,5-di(pyridin-4-yl)-4H-1,2,4-triazole) have been gram-scale prepared under solvothermal conditions. Structural analysis reveals that mac manages Co(ii) ions to form 1-D chains, which are further extended via 4,4-bpt connectors into a noninterpenetrating 3D framework architecture. It was found that 1 can be as a heterogeneous catalyst for multiple organic reactions, such as azide-alkyne cycloaddition and Friedel-Crafts reactions with good isolated yields and good recycle runs (at least five times without substantial degradation). Additionally, 1 can promote hydrosilylation of alkynes under harsh conditions with moderate yield. This journal is

Dipolar HCP materials as alternatives to DMF solvent for azide-based synthesis

Hypercrosslinked polymers HCP-DMF and HCP-DMF-SO3H containing abundant and flexible DMF moieties were designed and synthesized. Benefitting from the solvation microenvironment provided by the pseudo-DMF moities, the polar HCPs manifested outstanding performances in the conversions of NaN3 to benzylic azides and 1,2,3-triazoles in EtOH (95%), respectively, avoiding the use of risky DMF and improving the separation processes of the products.

Metal-free Synthesis of β-Nitrostyrenes via DDQ-Catalyzed Nitration

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