10184-64-2Relevant academic research and scientific papers
C-H hydroxylation of phosphonates with oxygen in [bmIm]OH to produce quaternary α-hydroxy phosphonates
Li, Xiangguang,Jin, Cheng,Gu, Lijun
, p. 2443 - 2447 (2015)
A highly efficient and mild [bmIm]OH-catalyzed α-hydroxylation of phosphonates using O2 as the oxygen source is described. The employment of ionic liquid under mild reaction conditions makes this transformation green and practical. Especially, this reaction provided a novel and convenient methodology for the construction of quaternary α-hydroxy phosphonates.
Lithium perchlorate diethyl ether solution: A highly efficient media for the abramov reaction
Azizi, Najmedin,Saidi, Mohammad R.
, p. 1255 - 1259 (2003)
The α-hydroxy phosphonates are readily prepared by treating aromatic or aliphatic aldehydes and ketones with trialkylphosphite in the presence of trimethylsilylchloride in a very short time and in almost quantitative yields.
Synthesis of quaternary α-hydroxy phosphonates via direct hydroxylation of phosphonate compounds
Liu, Jiyan,Wang, Wei,Wang, Rui,Gu, Lijun
supporting information, p. 559 - 562 (2015/05/27)
It was found for the first time that Cs2CO3 serves as highly efficient catalyst for the direct hydroxylation reactions of phosphonates under mild conditions. This reaction provides an efficient approach to quaternary α-hydroxy phosph
The catalytic aerobic synthesis of quaternary α-hydroxy phosphonates via direct hydroxylation of phosphonate compounds
Gu, Lijun,Jin, Cheng,Zhang, Hongtao
supporting information, p. 1579 - 1582 (2015/03/18)
A highly efficient Cu-catalyzed direct hydroxylation of phosphonate compounds has been developed. This transformation provides a powerful method for the synthesis of quaternary α-hydroxy phosphonates in good yields. The direct transformation process, regiospecific selectivity, and good tolerance to a variety of substituents make it an alternative approach to the reported protocols.
MgCl2/Et3N base system as a new catalyst for the synthesis of α-hydroxyphosphonate
Tajbakhsh, Mahmood,Khaksar, Samad,Tafazoli, Zahra,Bekhradnia, Ahmadreza
experimental part, p. 827 - 829 (2012/05/21)
An efficient and simple synthesis of α-hydroxyphosphonates via reaction of aldehydes and ketones with dimethylphosphite in the presence of MgCl2/Et3N base system is reported. The use of readily available and easy to handle reagent MgCl2/Et3N makes this method simple, convenient, and practical. Copyright
Pyridine 2,6-dicarboxylic acid as a bifunctional organocatalyst for hydrophosphonylation of aldehydes and ketones in water
Jahani, Fatemeh,Zamenian, Behi,Khaksar, Samad,Tajbakhsh, Mahmood
experimental part, p. 3315 - 3318 (2010/11/18)
A novel organocatalytic, direct synthesis of α-hydroxy phosphonates via reaction of aldehydes and ketones with trimethylphosphite in the presence of catalytic amounts of pyridine 2,6-dicarboxylic acid in water is reported. The method is simple, cost-effec
