1018545-27-1

Basic information

• Product Name: [3-(2,4-dichloro-phenyl)-5-methyl-isoxazol-4-yl]-methanol
• Synonyms: [3-(2,4-dichloro-phenyl)-5-methyl-isoxazol-4-yl]-methanol
• CAS NO: 1018545-27-1
• Molecular Weight: 258.104
• Mol File: 1018545-27-1.mol

Chemical Properties

• CAS DataBase Reference: [3-(2,4-dichloro-phenyl)-5-methyl-isoxazol-4-yl]-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: [3-(2,4-dichloro-phenyl)-5-methyl-isoxazol-4-yl]-methanol(1018545-27-1)
• EPA Substance Registry System: [3-(2,4-dichloro-phenyl)-5-methyl-isoxazol-4-yl]-methanol(1018545-27-1)

Safety Data

• Hazardous Substances Data: 1018545-27-1(Hazardous Substances Data)

Upstream product

• 29203-60-9 2,4-dichloro-N-hydroxybenzenecarboximidoyl chloride 
• 4402-77-1 3-(2,4-dichloro-phenyl)-5-methyl-isoxazole-4-carboxylic acid methyl ester 

Downstream Products

• 635681-04-8 2-{acetoxy-[3-(2,4-dichlorophenyl)-5-methylisoxazol-4-yl]methyl}acrylic acid methyl ester 
• 635681-09-3 acetic acid 2-cyano-1-[3-(2,4-dichlorophenyl)-5-methylisoxazol-4-yl]allyl ester 
• 627882-18-2 2-{[3-(2,4-dichlorophenyl)-5-methylisoxazol-4-yl]hydroxymethyl}acrylic acid methyl ester 
• 635680-66-9 2-{[3-(2,4-dichlorophenyl)-5-methylisoxazol-4-yl]hydroxymethyl}acrylonitrile 
• 635680-06-7 3-(2,4-dichloro-phenyl)-5-methyl-isoxazole-4-carbaldehyde 

Relevant articles and documents

Highly substituted isoxazoles: The Baylis-Hillman reaction of substituted 4-isoxazolecarbaldehydes and attempted cyclization to isoxazole-annulated derivatives

In an attempt to understand the effect of position of the formyl group on the efficiency of Baylis-Hillman reaction within isoxazolecarbaldehydes, the reactions of substituted 4-isoxazolecarbaldehydes to obtain highly substituted isoxazoles are described. Attempts to obtain isoxazole-annulated derivatives from these Baylis-Hillman adducts involving SNR′-SNAr substitution strategy are also described.