101876-89-5

Basic information

• Product Name: Benzenemethanamine, a-methyl-N-(3-phenyl-2-propenylidene)-
• CAS NO: 101876-89-5
• Molecular Formula: C17H17N
• Molecular Weight: 235.329
• Mol File: 101876-89-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzenemethanamine, a-methyl-N-(3-phenyl-2-propenylidene)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, a-methyl-N-(3-phenyl-2-propenylidene)-(101876-89-5)
• EPA Substance Registry System: Benzenemethanamine, a-methyl-N-(3-phenyl-2-propenylidene)-(101876-89-5)

Safety Data

• Hazardous Substances Data: 101876-89-5(Hazardous Substances Data)

Upstream product

• 98-80-6 phenylboronic acid 
• 100-52-7 benzaldehyde 
• 104-55-2 3-phenyl-propenal 
• 618-36-0 rac-methylbenzylamine 

Relevant articles and documents

Silylative Reductive Amination of α,β-Unsaturated Aldehydes: A Convenient Synthetic Route to β-Silylated Secondary Amines

Described here is a reductive amination/hydrosilylation cascade of α,β-unsaturated aldehydes mediated by a Lewis acidic borane catalyst. The present reaction system provides an one-pot synthetic route towards β-silylated secondary amines that have not been accessible by other previous catalysis. Comparative 1H NMR studies on the silylative reduction of enimines revealed that steric bulkiness of primary amine reactants strongly affects both catalytic efficiency and regioselectivity. This strategy was applicable to a broad range of substrates and amenable to one-pot gram-scale synthesis. Moreover, a diastereoselective introduction of the β-silyl group was also found to be feasible (d.r. up to 71:29).