101890-49-7

Basic information

• Product Name: 2-(5-phenoxypentyl)-1H-isoindole-1,3(2H)-dione
• Synonyms: 2-(5-phenoxypentyl)-1H-isoindole-1,3(2H)-dione
• CAS NO: 101890-49-7
• Molecular Weight: 309.365
• Mol File: 101890-49-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(5-phenoxypentyl)-1H-isoindole-1,3(2H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5-phenoxypentyl)-1H-isoindole-1,3(2H)-dione(101890-49-7)
• EPA Substance Registry System: 2-(5-phenoxypentyl)-1H-isoindole-1,3(2H)-dione(101890-49-7)

Safety Data

• Hazardous Substances Data: 101890-49-7(Hazardous Substances Data)

Upstream product

• 954-81-4 N-(5-bromopentyl)phthalimide 
• 108-95-2 phenol 
• 111-24-0 1,5-dibromo-pentane 
• 136918-14-4 phthalimide 

Downstream Products

• 1350730-45-8 C₃₀H₃₁N₂O₄⁽¹⁺⁾*Cl^(1-) 
• 16728-67-9 5-phenoxypentylamine 
• 103644-25-3 N-(5-{4-[bis-(2-hydroxy-ethyl)-amino]-phenoxy}-pentyl)-phthalimide 
• 103642-07-5 N-{5-[4-(2-methoxy-ethylamino)-phenoxy]-pentyl}-phthalimide 
• 102319-97-1 2-[5-(4-amino-phenoxy)-pentyl]-(3ar,7ac)-hexahydro-isoindole-1,3-dione 
• 103267-35-2 N,N'-bis-[5-(4-nitro-phenoxy)-pentyl]-phthalamide 
• 109037-66-3 (2,4-dichloro-phenoxy)-acetic acid-[5-(4-nitro-phenoxy)-pentylamide] 
• 102313-88-2 N-[5-(4-nitro-phenoxy)-pentyl]-[1]naphthamide 
• 110047-69-3 4-methoxy-benzoic acid-[5-(4-nitro-phenoxy)-pentylamide] 
• 102164-88-5 phenoxy-acetic acid-[5-(4-nitro-phenoxy)-pentylamide] 
• 110049-64-4 3-methoxy-benzoic acid-[5-(4-nitro-phenoxy)-pentylamide] 
• 110047-68-2 2-methoxy-benzoic acid-[5-(4-nitro-phenoxy)-pentylamide] 
• 102164-74-9 phenyl-acetic acid-[5-(4-nitro-phenoxy)-pentylamide] 
• 102008-71-9 phenoxy-acetic acid-[5-(4-amino-phenoxy)-pentylamide] 

Relevant articles and documents

Synthesis, biological evaluation of 9-N-substituted berberine derivatives as multi-functional agents of antioxidant, inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation

A series of 9-N-substituted berberine derivatives were synthesized and biologically evaluated as antioxidant and inhibitors of acetylcholinesterase (AChE), butyrylcholinesterase and amyloid-β aggregation. Most of these compounds exhibited very good antioxidant activities, inhibitive activities of AChE and amyloid-β aggregation. Among them, compound 8d, (o-methylphenethyl)amino linked at the 9-position of berberine, was found to be a good antioxidant (with 4.05 μM of Trolox equivalents), potent inhibitor of AChE (an IC50 value of 0.027 μM), and high active inhibitor of amyloid-β aggregation (an IC50 value of 2.73 μM).