101931-10-6

Basic information

• Product Name: 4-[2-(5-Ethyl-pyridin-2-yl)-3-hydroxypropoxy]nitrobenzene
• CAS NO: 101931-10-6
• Molecular Weight: 302.33
• Mol File: 101931-10-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[2-(5-Ethyl-pyridin-2-yl)-3-hydroxypropoxy]nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[2-(5-Ethyl-pyridin-2-yl)-3-hydroxypropoxy]nitrobenzene(101931-10-6)
• EPA Substance Registry System: 4-[2-(5-Ethyl-pyridin-2-yl)-3-hydroxypropoxy]nitrobenzene(101931-10-6)

Safety Data

• Hazardous Substances Data: 101931-10-6(Hazardous Substances Data)

Upstream product

• 127676-18-0 2-(5-ethylpyridin-2-yl)-1-propan-1,3-diol 
• 350-46-9 4-Fluoronitrobenzene 

Relevant articles and documents

Studies on antidiabetic agents. Synthesis and hypoglycemic activity of 5-[4-(pyridylalkoxy)benzyl]-2,4-thiazolidinediones

The synthesis of a series of 5-[4-(pyridylalkoxy)benzyl]-2,4-thiazolidinediones is described. These compounds were evaluated for hypoglycemic and hypolipidemic activities in genetically obese and diabetic mice, yellow KK. 2-(2-Pyridyl)alkoxy derivatives were found to have much better hypoglycemic and hypolipidemic activities than 2-(3-pyridyl)- and 2-(4-pyridyl)alkoxy derivatives or even the previously reported compound, ciglitazone. The introduction of a hydroxyl group at the 2-position of the ethoxy chain potentiated the activities. Among the potent compounds, pioglitazone (AD-4833) was selected as a candidate compound.