101935-40-4 Usage
Description
2-Bromo-3-nitrophenol is a chemical compound characterized by the molecular formula C6H4BrNO3. It is a yellow crystalline solid known for its role as an intermediate in the synthesis of various products, including pharmaceuticals, dyes, and agrochemicals. This versatile building block in organic chemistry is primarily produced through the nitration of 2-bromophenol. Due to its toxic nature, it requires careful handling to prevent ingestion or inhalation, which can be harmful.
Uses
Used in Pharmaceutical Industry:
2-Bromo-3-nitrophenol is used as a chemical intermediate for the synthesis of pharmaceuticals, contributing to the development of new drugs and medicines.
Used in Dye Industry:
It serves as a starting material in the production of dyes, playing a crucial role in the creation of colorants for various applications.
Used in Agrochemical Industry:
2-Bromo-3-nitrophenol is utilized as an intermediate in the synthesis of agrochemicals, aiding in the development of products for agricultural use.
Used in Organic Chemistry:
As a versatile building block, 2-Bromo-3-nitrophenol is used in the production of other organic compounds, facilitating the advancement of organic chemistry research and applications.
Used in Antimicrobial Applications:
2-Bromo-3-nitrophenol has demonstrated potential biological activity and is being studied for its antimicrobial properties, which could lead to its use in combating microbial infections.
Used in Antitumor Applications:
2-Bromo-3-nitrophenol is also being investigated for its antitumor properties, indicating a possible role in cancer research and treatment development.
Check Digit Verification of cas no
The CAS Registry Mumber 101935-40-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,1,9,3 and 5 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 101935-40:
(8*1)+(7*0)+(6*1)+(5*9)+(4*3)+(3*5)+(2*4)+(1*0)=94
94 % 10 = 4
So 101935-40-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H4BrNO3/c7-6-4(8(10)11)2-1-3-5(6)9/h1-3,9H
101935-40-4Relevant articles and documents
Chemoselectivity in the Kosugi-Migita-Stille coupling of bromophenyl triflates and bromo-nitrophenyl triflates with (ethenyl)tributyltin
Ansari, Nurul N.,Cummings, Matthew M.,S?derberg, Bj?rn C.G.
, p. 2547 - 2560 (2018/04/20)
Kosugi-Migita-Stille cross coupling reactions of (ethenyl)tributyltin with all isomeric permutations of bromophenyl triflate and bromo-nitrophenyl triflate were examined in order to determine the chemoselectivity of carbon-bromine versus carbon-triflate bond coupling under different reaction conditions. In general, highly selective carbon-bromine bond cross couplings were observed using for example bis(triphenylphosphine)palladium dichloride (2 mol-%) in 1,4-dioxane at reflux. In contrast, reactions using the same pre-catalyst but in the presence of a three-fold excess of lithium chloride in N,N-dimethylformamide at ambient temperature were in most cases selective for coupling at the carbon-triflate bond. Overall, isolated yields and the selectivity for carbon-bromine bond coupling were significantly higher compared to carbon-triflate bond coupling.
CHEMICAL COMPOUNDS
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Page/Page column 69-70, (2009/09/05)
A compound of the formula (I) where, for example, W, X and Y are each CH; R1 and R6, independently of each other, are for example, selected from the group consisting of H, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C1-C6-alkoxy, C3-C
DI-SUBSTITUTED PHENYL COMPOUNDS
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Page/Page column 59-60; 91, (2010/01/30)
Di-substituted phenyl compounds which are inhibitors of phosphodiesterase 10 are described as are processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of mammals, including human(s) f
