101970-29-0

Upstream product

• 600-22-6 pyruvic acid methyl ester 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 100-66-3 methoxybenzene 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 124-38-9 carbon dioxide 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 74-88-4 methyl iodide 

Downstream Products

• 50415-68-4 methyl 2-(4-methoxyphenyl)prop-2-enoate 
• 937255-91-9 (+/-)-methyl 2-methoxy-2-(4-methoxyphenyl)propionate 
• 937255-83-9 (+/-)-2-methoxy-2-(4-methoxyphenyl)propionic acid 
• 344257-61-0 3-(4-methoxyphenyl)-1-propylpiperidine 
• 459453-70-4 3-(4-methoxyphenyl)-1-propylpiperidin-2-one 
• 459453-67-9 3-(4-methoxyphenyl)-5-[(4-methylphenyl)sulfonyl]-1-propyl-1,2,3,4-tetrahydropyridin-2-one 
• 459453-63-5 3-(4-methoxyphenyl)-5-[(4-methylphenyl)sulfonyl]-1-propylpiperidine-2,6-dione 

Relevant academic research and scientific papers

Electrocatalytic carboxylation of aromatic ketones with carbon dioxide in ionic liquid 1-butyl-3-methylimidazoliumtetrafluoborate to α-hydroxy- carboxylic acid methyl ester

A new electrochemical procedure for the electrocatalytic carboxylation of aromatic ketones with carbon dioxide in ionic liquid, 1-butyl-3- methylimidazolium tetrafluoborate (BMIMBF4), to α- hydroxycarboxylic acid methyl ester was investigated for the first time. The electrochemical behavior of acetophenone in BMIMBF4 was studied by cyclic voltammetry with a reduction peak at -1.9 V (vs. Ag). The electrolyses experiments were carried out in an undivided cell under mild conditions without any toxic solvents, catalysts and supporting electrolytes, followed by addition of an alkylating agent, affording the α-hydroxycarboxylic acid methyl ester in a moderate yield (62%). The results showed that the yields were strongly affected by various factors: temperature, current density, charge passed, electrode material and substrate concentration. Moreover, the ionic liquid was successfully recycled for this reaction.

Conformational analysis of MαNP esters, powerful chiral resolution and 1H NMR anisotropy tools - aromatic geometry and solvent effects on Δδ values

The MαNP acid method is very powerful for the preparation of enantiopure alcohols by resolution and the simultaneous determination of their absolute configurations by the 1H NMR anisotropy effect, where the syn-syn conformation is taken as the

Highly regioselective Friedel-Crafts reactions of electron-rich aromatic compounds with pyruvate catalyzed by Lewis acid-base: Efficient synthesis of pesticide cycloprothrin

An efficient synthesis of aromatic lactate esters is reported via highly regioselective Friedel-Crafts reactions of electron-rich aromatic compounds with pyruvate ester promoted by TiCl4 in the presence of basic Al 2O3. The utility of the reaction is shown by the efficient synthesis of the pesticide cycloprothrin in high yield.

Electroreductive acylation of aromatic ketones with acylimidazoles

The intermolecular reductive coupling of aromatic ketones with acylimidazoles was effected by electroreduction in the presence of chlorotrimethylsilane and gave α-trimethylsiloxy ketones and esters. The best result was obtained using Bu4NPF6 as a supporting electrolyte and a Pb cathode in THF. The α-trimethylsiloxy-containing products were transformed to the corresponding α-hydroxy ketones and esters by treatment with TBAF in THF. This method was also effective for the intramolecular reductive coupling of δ- and ε-keto acylimidazoles.

New synthesis of 3-aryl-N-n-propyl-piperidines

The synthesis of 3-aryl-N-n-propyl-piperidines is described in six steps starting from α-sulfonyl acetamide via the formal [3+3] cycloaddition reaction.