101990-44-7

Basic information

• Product Name: N-[(6-chloropyridin-3-yl)methyl]ethane-1,2-diamine
• Synonyms: 1,2-ethanediamine, N1; N-[(6-Chloropyridin-3-yl)methyl]ethane-1,2-diamine
• CAS NO: 101990-44-7
• Molecular Formula: C₈H₁₂ClN₃
• Molecular Weight: 185.654
• Mol File: 101990-44-7.mol
• Article Data: 28

Chemical Properties

• Boiling Point: 323.992°C at 760 mmHg
• Flash Point: 149.745°C
• Density: 1.187g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.56
• CAS DataBase Reference: N-[(6-chloropyridin-3-yl)methyl]ethane-1,2-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(6-chloropyridin-3-yl)methyl]ethane-1,2-diamine(101990-44-7)
• EPA Substance Registry System: N-[(6-chloropyridin-3-yl)methyl]ethane-1,2-diamine(101990-44-7)

Safety Data

• Hazardous Substances Data: 101990-44-7(Hazardous Substances Data)

Upstream product

• 69045-78-9 2-chloro-5-(Trichloromethyl)-pyridine 
• 70258-18-3 2-chloro-5-(chloromethyl)pyridine 
• 107-15-3 ethylenediamine 

Downstream Products

• 115970-17-7 Desnitro-imidacloprid 
• 1254942-04-5 (Z)-N-[2-[1-[(6-chloropyridin-3-yl)methyl]-2-imidazolidinylidene]-2-nitrothioacetyl]benzamide 
• 1254942-11-4 (Z)-N-[1-[(6-chloropyridin-3-yl)methyl]-2,3-dihydro-7-nitro-1H-imidazo[1,2-b]isothiazol-6-ylidene]benzamide 
• 141631-47-2 2-{1-[(6-chloropyridin-3-yl)methyl]imidazolidin-2-ylidene}acetonitrile 

Relevant articles and documents

Synthesis and chiral purification of 14C-labeled novel neonicotinoids, paichongding

Paichongding, a novel neonicotinoids pesticide with excellent insecticidal activity against imidacloprid-resistant brown planthopper, has been sold in the Chinese market as new pesticide. [14C]Paichongding was proposed as a tracer to support the further study to elucidate the metabolism of the commercialized pesticide. This paper describes an efficient synthesis of [ 14C]paichongding in five radiochemical steps from [ 14C]nitromethane (1). Then the four diastereoisomers (a, b, c, and d) were separated by preparative chiral HPLC and characterized by HPLC and HPLC-LSC. This methodology could be utilized in the syntheses of other 14C-labeled nitromethylene neonicotinoids derivatives.

Synthesis, insecticidal activity, and QSAR of novel nitromethylene neonicotinoids with tetrahydropyridine fixed cis configuration and exo-ring ether modification

To keep the nitro group in the cis position, a series of nitromethylene neonicotinoids containing a tetrahydropyridine ring with exo-ring ether modifications were designed and synthesized. All of the compounds were characterized and confirmed by 1/s

Method for synthesizing imidacloprid at high yield

The invention provides a method for synthesizing imidacloprid at a high yield. 2-chloro-5-chloromethylpyridine, ethylenediamine and cyanogen halide, which are used as raw materials, are aminated, cyclized and nitrified to synthesize the imidacloprid. The method has the advantages of high safety in the production process, good purity and high yield of the product, and easiness in industrializationrealization.

Synthesis and insecticidal evaluation of tetrahydroimidazo[1,2-a]pyridin-5(1H)-one derivatives

A series of novel tetrahydroimidazo[1,2-a]pyridine-5(1H)-one derivatives containing a electronegative pharmacophore (=CNO2) were synthesized via practical aza-ene reaction and characterized by 1H NMR, 13C NMR, 19F NMR and HRMS. Preliminary bioassays showed that some of the target compounds exhibited good insecticidal activity against brown planthopper (Nilaparvata lugens) and cowpea aphids (Aphis craccivora) at 500 mg L-1. Among them, compound 11h was active against brown planthopper at 100 mg L-1. The insecticidal activities varied significantly depending on the types and patterns of the substituents, which provided guidance for further investigation on structure modifications.