1019918-39-8Relevant articles and documents
GPR52 MODULATOR COMPOUNDS
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Page/Page column 35; 46, (2021/09/17)
The disclosures herein relate to novel compounds of Formula (1): and salts thereof, wherein X, Y, R1, R2, R3 and R4 are defined herein, and their use in treating, preventing, ameliorating, controlling or reducing the risk of disorders associated with GPR52 receptors.
INHIBITORS OF KEAP1-Nrf2 PROTEIN-PROTEIN INTERACTION
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Paragraph 1969-1970, (2020/03/01)
Sultam compounds, pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with the KEAP1-Nrf2 interaction, such as inflammatory bowel disease, including Crohn's disease and ulcerative colitis.
SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE
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Paragraph 000463; 000514, (2019/06/05)
The present invention provides novel heteroaryl compounds, pharmaceutical acceptable salts and formulations thereof. They are useful in preventing, managing, treating or lessening the severity of a protein kinase-mediated disease. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of protein kinase-mediated disease.