1020074-00-3Relevant academic research and scientific papers
Palladium-catalyzed hydroarylation of alkynes with arenediazonium salts
Cacchi, Sandro,Fabrizi, Giancarlo,Goggiamani, Antonella,Persiani, Daniela
, p. 1597 - 1600 (2008)
The palladium-catalyzed hydroarylation of arenediazonium tetrafluoroborates with alkynes in the presence of triphenylsilane affords stereoselectively hydroarylation products in moderate to high yields. The reaction tolerates a variety of substituents including keto, ester, cyano, and nitro groups and can be performed as a one-pot procedure generating the arenediazonium salt in situ. With ethyl phenylpropynoate as the starting alkyne, the hydroarylation affords ethyl (2)-2-arylcinnamates stereo- and regioselectively.
