102025-06-9Relevant academic research and scientific papers
Concise synthesis of α-cyano tetrahydroisoquinolines with a quaternary centerviaStrecker reaction
Han, Weiwei,Ji, Yue,Wang, Sichang,Wei, Yitao,Wu, Ya,Xiao, Pei,Yang, Penghui,Zhang, Keliang,Zhang, Xue
, p. 38712 - 38716 (2021/12/21)
A concise synthesis of α-cyano tetrahydroisoquinolines with a quaternary centerviathe Strecker reaction was successfully realized by employing TMSCN as cyano source and KF as fluoride source, furnishing the products with up to 99% yield. An isomerization
