52250-50-7 Usage
Description
1-Phenyl-3,4-dihydroisoquinoline is an organic compound belonging to the isoquinoline family. It is characterized by its unique molecular structure, which features a phenyl group attached to a dihydroisoquinoline ring. 1-Phenyl-3,4-dihydroisoquinoline is known for its potential applications in various fields due to its chemical properties.
Uses
1. Used in Pharmaceutical Industry:
1-Phenyl-3,4-dihydroisoquinoline is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications.
2. Used in Chemical Synthesis:
1-Phenyl-3,4-dihydroisoquinoline serves as a valuable building block in the preparation of a wide range of organic compounds, including 1,2,3,4-Tetrahydro-2-methyl-1-phenyl-1-isoquinolinecarbonitrile derivatives. These derivatives can be further utilized in the development of new chemical products with diverse applications.
3. Used in Research and Development:
1-Phenyl-3,4-dihydroisoquinoline is also employed in research and development laboratories for studying its chemical properties and potential applications. Its unique structure makes it an interesting subject for scientific investigation, which could lead to the discovery of new compounds and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 52250-50-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,2,5 and 0 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 52250-50:
(7*5)+(6*2)+(5*2)+(4*5)+(3*0)+(2*5)+(1*0)=87
87 % 10 = 7
So 52250-50-7 is a valid CAS Registry Number.
InChI:InChI=1/C15H13N/c1-2-7-13(8-3-1)15-14-9-5-4-6-12(14)10-11-16-15/h1-9H,10-11H2
52250-50-7Relevant articles and documents
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Parham et al.
, p. 1606 (1978)
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Tf2O/TTBP (2,4,6-Tri-tert-butylpyrimidine): An Alternative Amide Activation System for the Direct Transformations of Both Tertiary and Secondary Amides
He, Qian,Ye, Jian-Liang,Xu, Fang-Fang,Geng, Hui,Chen, Ting-Ting,Chen, Hang,Huang, Pei-Qiang
, (2021/09/28)
Ten types of Tf2O/TTBP-mediated amide transformation reactions were investigated. The results showed that compared with pyridine derivatives 2,6-di-tert-butyl-4-methylpyridine (DTBMP) and 2-fluoropyridine (2-F-Pyr.), TTBP can serve as an alternative amide activation system for the direct transformation of both secondary and tertiary amides. For most surveyed examples, higher or comparable yields were generally obtained. In addition, Tf2O/TTBP combination was used to promote the condensation reactions of 2-(tert-butyldimethylsilyloxy)furan (TBSOF) with both tertiary and secondary amides, the one-pot reductive Bischler-Napieralski-type reaction of tertiary lactams, and Movassaghi and Hill's modern version of the Bischler-Napieralski reaction. The value of the Tf2O/TTBP-based methodology was further demonstrated by the concise and high-yielding syntheses of several natural products.
Diprotonative stabilization of ring-opened carbocationic intermediates: conversion of tetrahydroisoquinoline to triarylmethanes
Kurouchi, Hiroaki
, p. 8313 - 8316 (2020/08/17)
Superacid-promoted conversion of tetrahydroisoquinolines to triarylmethanes via tandem reactions of C-N bond scission, Friedel-Crafts alkylation, C-O bond scission, and electrophilic aromatic amidation was developed. Dication formation was important for stabilizing the ring-opened carbocationic intermediate, which is a new role for diprotonation in reaction mechanisms. This journal is