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11α,17α,21-Trihydroxy-pregn-5-ene-3,20-dione 3,20-Diethylene Ketal is a complex organic compound belonging to the steroid family. It is characterized by its unique molecular structure, featuring three hydroxyl groups at the 11α, 17α, and 21 positions, and a dione group at the 3 and 20 positions. Additionally, it has a diethylene ketal functional group, which contributes to its chemical properties. This off-white solid is an intermediate in the synthesis of Epi Hydrocortisone derivatives, a class of corticosteroids with potent anti-inflammatory and immunosuppressive properties.

102030-55-7

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102030-55-7 Usage

Uses

Used in Pharmaceutical Industry:
11α,17α,21-Trihydroxy-pregn-5-ene-3,20-dione 3,20-Diethylene Ketal is used as an intermediate in the synthesis of Epi Hydrocortisone derivatives for its role in the production of corticosteroids. These derivatives are essential in the treatment of various inflammatory and autoimmune conditions, such as asthma, allergies, and rheumatoid arthritis, due to their potent anti-inflammatory and immunosuppressive effects.
Used in Chemical Research:
As a complex steroidal compound, 11α,17α,21-Trihydroxy-pregn-5-ene-3,20-dione 3,20-Diethylene Ketal can also be utilized in chemical research for the development of novel steroidal drugs and understanding the structure-activity relationships of steroidal compounds. Its unique molecular structure makes it a valuable tool for exploring new therapeutic applications and advancing the field of medicinal chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 102030-55-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,0,3 and 0 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 102030-55:
(8*1)+(7*0)+(6*2)+(5*0)+(4*3)+(3*0)+(2*5)+(1*5)=47
47 % 10 = 7
So 102030-55-7 is a valid CAS Registry Number.

102030-55-7Relevant academic research and scientific papers

Etiprednol dicloacetate, a new soft glucocorticoid drug candidate. Development of chemistry

Csanadi,Horvath,Szekeres,Hasko,Ila,Ivanics,Patthy,Salat,Seres,Pallagi,Toth,Szederkenyi,Konya,Tegdes,Bodor,Zubovics, Zoltan

, p. 349 - 359 (2007/10/03)

During development of chemistry of the soft drug candidate etiprednol dicloacetate (BNP-166) 1) optimization studies on the three-step chemical synthesis resulted in a process that could be scaled-up to the kg level, 2) the impurity profile was determined, 3) synthetic routes were developed for the preparation of the radiolabeled target compound, and 4) a series of hydroxylated metabolites was prepared.

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