1020673-57-7Relevant academic research and scientific papers
Asymmetric hydrogenation for the synthesis of 2-substituted chiral morpholines
Li, Mingxu,Zhang, Jian,Zhang, Wanbin,Zhang, Zhenfeng,Zhou, Fengfan,Zou, Yashi
, p. 15061 - 15066 (2021/12/09)
Asymmetric hydrogenation of unsaturated morpholines has been developed by using a bisphosphine-rhodium catalyst bearing a large bite angle. With this approach, a variety of 2-substituted chiral morpholines could be obtained in quantitative yields and with excellent enantioselectivities (up to 99% ee). The hydrogenated products could be transformed into key intermediates for bioactive compounds. This journal is
POLYCYCLIC COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR
-
Page/Page column 11, (2008/12/05)
Compounds of formula (I) are disclosed. Compounds according to the invention are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treati
COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR
-
Page/Page column 19, (2008/06/13)
Compounds are provided which bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, the compounds having the general formula (I) wherein, R1, R2, A, Y, X, Ar1 and Ar2 have the meanings given in the specification, and the preparation and use thereof. The compounds are valuable CB2 receptor modulators.
