102069-48-7

Upstream product

• 86733-60-0 4,7-O-benzylidenevalidoxylamine A hexa-O-acetate 
• 86756-42-5 2,3,4',5',6',7'-hexa-O-benzyl-4,7-O-benzylidenevalidoxylamine A 
• 86733-61-1 2,3,4',5',6',7'-hexa-O-benzylvalidoxylamine A 
• 100-39-0 benzyl bromide 

Downstream Products

• 102069-49-8 2'',3'',4'',6''-tetra-O-acetyl-2,3,4',5',6',7'-hexa-O-benzyl-7-deoxyvalidamycin A 

Relevant academic research and scientific papers

Synthetic Studies on Antibiotic Validamycins. Part 11. Synthesis of Validamycin A

The antibiotic validamycin A (1a) has been synthesized for the first time (as its undeca-O-acetate) by glycosylation of the partially protected derivative (8) of the aglycone, validoxylamine A (2a), with 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl chloride (11), followed by deprotection, thereby establishing the structure previously assigned.The totally O-acetylated derivative (19) of 7-deoxyvalidamycin A has been synthesized in a similar fashion.