1020719-18-9 Usage
Uses
Used in Pharmaceutical Industry:
N-2-Benzyloxyphenyl α-Benzilidene-d5 Isobutyrylacetamide is used as a deuterated intermediate for the synthesis of Atorvastin, a drug specifically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Its deuterated nature may provide advantages in terms of stability, synthesis, and potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1020719-18-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,0,7,1 and 9 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1020719-18:
(9*1)+(8*0)+(7*2)+(6*0)+(5*7)+(4*1)+(3*9)+(2*1)+(1*8)=99
99 % 10 = 9
So 1020719-18-9 is a valid CAS Registry Number.
1020719-18-9Relevant academic research and scientific papers
Synthesis of deuterium-labeled atorvastatin and its metabolites for use as internal standards in a LC/MS/MS method developed for quantitation of the drug and its metabolites in human serum
Chen, Bang-Chi,Sundeen, Joseph E.,Guo, Peng,Bednarz, Mark S.,Hangeland, Jon J.,Ahmed, Syed Z.,Jemal, Mohammed
, p. 261 - 270 (2007/10/03)
D5-labeled isotopomers of atorvastatin, atorvastatin lactone and its hydroxy metabolites were synthesized as internal standards for use in a LC/MS/MS method developed for the simultaneous quantitative determination of atorvastatin and its hydroxy metabolites in human serum. d5-Atorvastatin and d5-atorvastatin lactone were prepared from d5-aniline whereas their corresponding hydroxy metabolites were synthesized using d5-benzaldehyde.
