1021-45-0

Basic information

• Product Name: Phosphoric acid, diethyl 1-phenylethenyl ester
• CAS NO: 1021-45-0
• Molecular Formula: C12H17O4P
• Molecular Weight: 256.238
• Mol File: 1021-45-0.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Phosphoric acid, diethyl 1-phenylethenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphoric acid, diethyl 1-phenylethenyl ester(1021-45-0)
• EPA Substance Registry System: Phosphoric acid, diethyl 1-phenylethenyl ester(1021-45-0)

Safety Data

• Hazardous Substances Data: 1021-45-0(Hazardous Substances Data)

Usage

General Description

Phosphoric acid, diethyl 1-phenylethenyl ester, also known as diethyl (E)-2-phenyl-2-propenoate, is a chemical compound commonly used as a flavoring agent in the food and beverage industry. It is often added to soft drinks and other carbonated beverages to give them a tangy, acidic taste. Phosphoric acid, diethyl 1-phenylethenyl ester is also used as a fragrance ingredient in perfumes and cosmetics, as well as in the production of plasticizers and resins. Additionally, it has been used in research and industrial applications as a reagent and intermediate in the synthesis of other organic compounds. However, it is important to note that this compound should be handled with care, as it can be irritating to the skin, eyes, and respiratory system, and may have harmful effects if ingested or inhaled.

Upstream product

• 2303-76-6 sodium diethyl phosphite 
• 70-11-1 α-bromoacetophenone 
• 88073-05-6 2-(2-phenyl-2-oxoethoxy)-2,3-dihydro-1H-isoindole-1,3-dione 
• 78-40-0 triethyl phosphate 
• 762-04-9 phosphonic acid diethyl ester 
• 122-52-1 triethyl phosphite 
• 98-81-7 1-bromovinylbenzene 
• 721-04-0 2-phenoxy-1-phenylethanone 
• 76387-53-6 1-Hydroxy-2-methylthio-1-phenylethanphosphonsaeurediethylester 
• 532-27-4 1-chloroacetophenone 
• 13716-45-5 diethyl trimethylsilyl phosphite 
• 100-52-7 benzaldehyde 
• 78610-05-6 diethyl α-(chloromethyl)-α-<(trimethylsilyl)oxy>benzylphosphonate 
• 3277-27-8 diethyl benzoylphosphonate 

Downstream Products

• 63762-91-4 2-<(3-Methoxyphenyl)thio>-1-phenylethanone 
• 82420-76-6 2-[(naphthalen-2-yl)sulfanyl]-1-phenylethanone 
• 16222-10-9 1-phenyl-2-(phenylthio)ethanone 
• 33046-45-6 1-phenyl-2-(p-tolylthio)ethanone 
• 67210-34-8 1-phenyl-2-phenylsulfanyl-ethanol 
• 13865-49-1 [2-(phenylsulfanyl)ethyl]benzene 
• 3406-03-9 2-(phenylsulfonyl)acetophenone 
• 13307-77-2 1,1-diphenyl-2-(phenylthio)ethan-1-ol 
• 7312-06-3 2-(4-bromophenylthio)-1-phenylethanone 
• 30168-33-3 2-[(4-chlorophenyl)thio]-1-phenylethanone 
• 101169-28-2 2-((3,4-dimethoxyphenyl)thio)-1-phenylethan-1-one 
• 882430-05-9 2-(2-bromophenylthio)-1-phenylethanone 
• 30089-54-4 2-<(2-Methoxyphenyl)thio>-1-phenylethanone 
• 19968-31-1 2-((3,4-dichlorophenyl)thio)-1-phenylethan-1-one 

Relevant articles and documents

-

-

Electrochemical Oxidative Difunctionalization of Alkenes to Access α-Oxygenated Ketones

Dioxygenation of alkenes was developed by the combination of electrochemical synthesis and aerobic oxidation, leading to easy accessibility of α-oxygenated ketones in an eco-friendly fashion. Using air as the oxygen source and the absence of transition metals were the critical features of this protocol. A wide range of alkenes and N-hydroxyimides were found to be compatible and provided α-oxygenated ketones in moderate to high yields.

Copper(I)-catalyzed oxidation of alkenes using molecular oxygen and hydroxylamines: Synthesis and reactivity of α-oxygenated ketones

The copper(I)-catalyzed oxidation of alkenes with molecular oxygen and N-hydroxyphthalimide (NHPI) or N-hydroxybenzotriazole (HOBt) provided α-oxygenated ketones. The reaction proceeded under a balloon of O2 at room temperature to furnish the dioxygenated products in 50-90% yield. These compounds, particularly the HOBt derivatives, can be further functionalized with phosphorus, nitrogen, and sulfur nucleophiles to give synthetically useful products.

Asymmetric hydrogenation of α- Or β-acyloxy α,β- unsaturated phosphonates catalyzed by a Rh(i) complex of monodentate phosphoramidite

The Rh(i) complex of a monodentate phosphoramidite bearing a primary amine moiety (DpenPhos) has been disclosed to be highly efficient for the asymmetric hydrogenation of a variety of α- or β-acyloxy α,β- unsaturated phosphonates, providing the corresponding biologically important chiral α- or β-hydroxy phosphonic acid derivatives with excellent enantioselectivities (90->99% ee).