102125-62-2 Usage
General Description
N-Isopropyl-4-piperidinecarboxamide hydrochloride is a chemical compound that is a derivative of piperidinecarboxamide. It is commonly used as an intermediate in the synthesis of various pharmaceutical compounds. This chemical has shown potential as an analgesic and anticonvulsant, and has been studied for its potential therapeutic applications in the treatment of neurological disorders. N-Isopropyl-4-piperidinecarboxamide hydrochloride is typically used in research and development laboratories for the synthesis of new drug candidates and is not commonly found in commercial products.
Check Digit Verification of cas no
The CAS Registry Mumber 102125-62-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,1,2 and 5 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 102125-62:
(8*1)+(7*0)+(6*2)+(5*1)+(4*2)+(3*5)+(2*6)+(1*2)=62
62 % 10 = 2
So 102125-62-2 is a valid CAS Registry Number.
102125-62-2Relevant articles and documents
Improving selectivity preserving affinity: New piperidine-4-carboxamide derivatives as effective sigma-1-ligands
Zampieri, Daniele,Laurini, Erik,Vio, Luciano,Fermeglia, Maurizio,Pricl, Sabrina,Wunsch, Bernhard,Schepmann, Dirk,Mamolo, Maria Grazia
, p. 797 - 808 (2015/02/19)
We report the design, synthesis and binding evaluation against 1 and 2 receptors of a series of new piperidine-4-carboxamide derivatives variously substituted on the amide nitrogen atom. Specifically, we assessed the effects exerted on receptor affinity by substituting the N-benzylcarboxamide group present on a series of compounds previously synthesized in our laboratory with different cyclic or linear moieties. The synthesized compounds 2a-o were tested to estimate their affinity and selectivity toward 1 and2 receptors. Very high 1 affinity (Ki Combining double low line 3.7 nM) and Ki2/Ki1 selectivity ratio (351) were found for the tetrahydroquinoline derivative 2k, featuring a 4-chlorobenzyl moiety linked to the piperidine nitrogen atom.
