102137-46-2

Basic information

• Product Name: 4-(pyridin-2-ylmethoxy)aniline
• Synonyms: 4-(pyridin-2-ylmethoxy)aniline;Albb-005559;4-(pyridin-2-ylmethoxy)aniline(SALTDATA: FREE);4-(Pyridine-2ylMethoxy)aniline;[4-(2-pyridylmethoxy)phenyl]amine;4-(2-pyridylmethoxy)aniline;2-[(4-Aminophenoxy)methyl]pyridine
• CAS NO: 102137-46-2
• Molecular Formula: C₁₂H₁₂N₂O
• Molecular Weight: 200.24
• Mol File: 102137-46-2.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 369.5 °C at 760 mmHg
• Flash Point: 177.3 °C
• Appearance: /
• Density: 1.18 g/cm³
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 4-(pyridin-2-ylmethoxy)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(pyridin-2-ylmethoxy)aniline(102137-46-2)
• EPA Substance Registry System: 4-(pyridin-2-ylmethoxy)aniline(102137-46-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 102137-46-2(Hazardous Substances Data)

Usage

General Description

4-(Pyridin-2-ylmethoxy)aniline is a chemical compound with the formula C12H12N2O. It is a substituted aniline derivative, containing a pyridine ring and a methoxy group attached to the second position of the pyridine ring. 4-(Pyridin-2-ylmethoxy)aniline is used in organic synthesis and medicinal chemistry, and it has been studied for its potential biological activities. Its structural features make it a valuable building block for the synthesis of various organic compounds, and it has shown promising activity in the development of pharmaceutical agents. Additionally, it can be used as a ligand in coordination chemistry and in the preparation of complex organic molecules. Overall, 4-(Pyridin-2-ylmethoxy)aniline has interesting chemical properties and potential applications in various fields, making it a compound of interest for further research and development.

Upstream product

• 103-90-2 4-acetaminophenol 
• 6959-47-3 2-chloromethylpyridine hydrochloride 
• 105350-45-6 N-acetyl-4-(pyrid-2-ylmethoxy)aniline 
• 852314-54-6 C₁₇H₂₀N₂O₃ 
• 350-46-9 4-Fluoronitrobenzene 
• 586-98-1 2-Hydroxymethylpyridine 
• 145654-42-8 2-(4-nitrophenoxymethyl)pyridine 

Downstream Products

• 1393835-36-3 1-(3-morpholinopropyl)-8-(4-(pyridin-2-ylmethoxy)phenylamino)oxazolo[4,5-g]quinazolin-2(1H)-one 
• 1166310-88-8 1-(3-chloropropyl)-3-[4-(2-pyridinylmethoxy)phenyl]urea 
• 1166310-86-6 1-(2-chloroethyl)-3-[4-(2-pyridinylmethoxy)phenyl]urea 
• 936351-48-3 4-(pyridin-2-ylmethoxy)-phenylamine hydrochloride 
• 936801-69-3 ethyl 6-methyl-5-(4-(pyridine-2-ylmethoxy)phenylcarbamoyl)-nicotinate 
• 936801-62-6 2-methyl-5-nitro-N-[4-(pyridin-2-ylmethoxy)-phenyl]-nicotinamide 
• 339071-61-3 N-[4-(pyridin-2-ylmethoxy) phenyl]-N'-hydroxyformamidine 

Relevant articles and documents

NAPHTHALENE DERIVATIVE

The present invention provides compounds which can regulate VCP activity. The present invention provides the compound of formula (I) (R is as defined in the description) or oxides, esters, prodrugs, pharmaceutically acceptable salts or solvates thereof. The compounds can regulate VCP activity, and thus are useful for treating VCP-mediated diseases such as neurodegenerative diseases.

Studies on novel 2-imidazolidinones and tetrahydropyrimidin-2(1H)-ones as potential TACE inhibitors: Design, synthesis, molecular modeling, and preliminary biological evaluation

Compounds belonging to the class of 2-imidazolidinones and tetrahydropyrimidin-2(1H)-ones were synthesized and evaluated for their TACE inhibitory activity. Most of the compounds showed very good TACE inhibitory activity. Docking study clearly indicates importance of the P1′ group of the inhibitor for the TACE inhibitory activity. This work proves that these two classes of molecules could be used as potential leads for the development of TACE inhibitors.

COMPOSITIONS AND TREATMENTS COMPRISING 5-LIPOXYGENASE-ACTIVATING PROTEIN INHIBITORS AND NITRIC OXIDE MODULATORS

Disclosed herein are compositions and compounds that combine an inhibitor of 5-lipoxygenase activating protein (FLAP) and a modulator of NO levels in a mammal. The NO modulator can be an agent that induces the production of NO in a mammal, or can be an ag