10215-30-2

Basic information

• Product Name: 1-Propanol, 2-propoxy-
• Synonyms: 1-Propanol, 2-propoxy-;2-Propoxy-1-Propanol
• CAS NO: 10215-30-2
• Molecular Formula: C₆H₁₄O₂
• Molecular Weight: 118.17
• Mol File: 10215-30-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 157.8°Cat760mmHg
• Flash Point: 50.2°C
• Appearance: /
• Density: 0.896g/cm³
• Vapor Pressure: 0.968mmHg at 25°C
• Refractive Index: 1.416
• PKA: 14.47±0.10(Predicted)
• CAS DataBase Reference: 1-Propanol, 2-propoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanol, 2-propoxy-(10215-30-2)
• EPA Substance Registry System: 1-Propanol, 2-propoxy-(10215-30-2)

Safety Data

• Hazardous Substances Data: 10215-30-2(Hazardous Substances Data)

Usage

General Description

1-Propanol, 2-propoxy- is a chemical compound with the formula C6H14O2. It is a colorless liquid that is used as a solvent and a synthetic intermediate in organic chemistry. It is also known by the name isopropoxypropanol and is commonly used in the production of coatings, inks, and cleaning products. It has a mild, ether-like odor and is highly flammable, so it should be handled with care. 1-Propanol, 2-propoxy- is considered to be a hazardous substance and should be used in well-ventilated areas and with appropriate safety measures in place.

InChI:InChI=1/C6H14O2/c1-3-4-8-6(2)5-7/h6-7H,3-5H2,1-2H3

Upstream product

• 57-55-6 propylene glycol 
• 71-23-8 propan-1-ol 
• 75-56-9 methyloxirane 

Relevant articles and documents

Catalytic deoxygenation of 1,2-propanediol to give n-propanol

Deoxygenation of 1,2-propanediol (1.0M in sulfolane) catalyzed by bis(dicarbonyl)(μhydrido)(pentamethylcyclopentadiene)ruthenium trifluoromethanesulfonate ({[Cp*Ru(CO)2]2(μ.-H)} +OTf-) (0.5 mol%) at 110°C under hydrogen (750 psi) in the presence of trifluoromethanesulfonic acid (HOTf) (60 mM) gives n-propanol as the major product, indicating high selectivity for deoxygenation of the internal hydroxy group over the terminal hydroxy group of the diol. The deoxygenation of 1,2-propanediol is strongly influenced by the concentration of acid, giving faster rates and proceeding to higher conversions as the concentration of HOTf is increased. Propionaldehyde was observed as an intermediate, being formed through acid-catalyzed dehydration of 1,2-propanediol. This aldehyde is hydrogenated to n-propanol through an ionic pathway involving protonation of the aldehyde, followed by hydride transfer from the neutral hydride, dicarbonyl(pentamethylcyclopentadiene)ruthenium hydride [Cp*Ru(CO)2H]. The proposed mechanism for the deoxygenation/hydrogenation reaction involves formation of a highly acidic dihydrogen complex [Cp*Ru(CO)2(η2-H 2)]+ OTf-.

METHODS OF CONVERTING POLYOLS

Methods for converting polyols are provided. The methods provided can include using a metal pincer catalyst (e.g., an iridium pincer catalyst) to remove at least one alcohol group from a polyol. The methods provided can include converting glycerol to 1,3-propanediol.

The Use of Proton-exchanged X-Type Zeolite in Catalysing Ring-opening Reactions of 2-Substituted Epoxides with Nucleophiles and its Effect on Regioselectivity

The use of proton-exchanged X-type zeolite in catalysing ring-opening reactions of 2-alkyl substituted epoxides with nucleophiles gives a high regioselectivity and functional-selective catalysis giving allylic products from allylic nucleophiles.Mechanistic aspects are discussed.