2-Propoxy-1-propanol

Base Information

• Chemical Name: 2-Propoxy-1-propanol
• CAS No.: 10215-30-2
• Molecular Formula: C6H14 O2
• Molecular Weight: 118.176
• Hs Code.: 2909499000
• UNII: EW9L6R146C
• DSSTox Substance ID: DTXSID70907178
• Nikkaji Number: J1.556.147E
• Wikidata: Q27277392
• Mol file: 10215-30-2.mol

Synonyms:2-PROPOXY-1-PROPANOL;1-Propanol, 2-propoxy-;2-propoxypropan-1-ol;10215-30-2;UNII-EW9L6R146C;EW9L6R146C;2-propoxypropanol;2-methyl-2-propyloxyethanol;SCHEMBL225743;2-METHYL-3-OXAHEXANOL;DTXSID70907178;PROPYLENE GLYCOL 2-PROPYL ETHER;(+/-)-2-PROPOXY-1-PROPANOL;2-PROPOXY-1-PROPANOL, (+/-)-;Q27277392

Chemical Property of 2-Propoxy-1-propanol

Chemical Property:

• Vapor Pressure: 0.968mmHg at 25°C
• Boiling Point: 157.8°Cat760mmHg
• PKA: 14.47±0.10(Predicted)
• Flash Point: 50.2°C
• PSA: 29.46000
• Density: 0.896g/cm³
• LogP: 0.79380
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 118.099379685
• Heavy Atom Count: 8
• Complexity: 45.8

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCOC(C)CO

Technology Process of 2-Propoxy-1-propanol

There total 4 articles about 2-Propoxy-1-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

propylene glycol (57-55-6,63625-56-9) → propan-1-ol (71-23-8) + 2-ethyl-4-methyl-1,3-dioxolane (4359-46-0) + Dipropyl ether (111-43-3) + 2-propoxy-1-propanol (10215-30-2) + 1-(1-propyloxy)propan-2-ol (1569-01-3) + propionaldehyde (123-38-6)

Guidance literature:

With bis(dicarbonyl)(μ-hydrido)(pentamethylcyclopentadiene)ruthenium trifluoromethanesulfonate; trifluorormethanesulfonic acid; hydrogen; In sulfolane; at 110 ℃; for 30h; under 38787.1 Torr; Solvent; Pressure; Concentration; Temperature; Time; regioselective reaction; Mechanism; Kinetics;

DOI:10.1002/adsc.200800685

Reference yield:

propylene glycol (57-55-6,63625-56-9) → propan-1-ol (71-23-8) + propyl propionate (106-36-5) + propane (74-98-6) + 2-propoxy-1-propanol (10215-30-2) + 1-(1-propyloxy)propan-2-ol (1569-01-3) + propionic acid (802294-64-0,79-09-4) + 1,3,5-trimethyl-benzene (108-67-8)

Guidance literature:

With [C₆H₃-2,6-(OP(tBu)2)2]IrH₂; trifluorormethanesulfonic acid; hydrogen; In 1,4-dioxane; at 125 ℃; under 5171.62 Torr; Autoclave;

Reference yield:

propylene glycol (57-55-6,63625-56-9) → propan-1-ol (71-23-8) + Dipropyl ether (111-43-3) + 2-propoxy-1-propanol (10215-30-2) + 1-(1-propyloxy)propan-2-ol (1569-01-3)

Guidance literature:

With trifluorormethanesulfonic acid; hydrogen; [{CpRu(CO)2}2(μ-H)](+)*OTf(-); cyclopenta-1,3-diene; In sulfolane; at 110 ℃; for 30h; under 39003.1 Torr; Product distribution;

DOI:10.1002/1521-3773(20011015)40:20<3887::AID-ANIE3887>3.0.CO;2-Q

upstream raw materials:

propan-1-ol

methyloxirane

propylene glycol

Refernces

• 1、 Rahmatpour, Ali,Zamani, Maryam. "MBA-cross-linked poly(N-vinyl-2-pyrrolidone)/ferric chloride macromolecular coordination complex as a novel and recyclable Lewis acid catalyst: Synthesis, characterization, and performance toward for regioselective ring-opening alcoholysis of epoxides". . . Retrieved 2021/09/30.
• 2、 Schlaf, Marcel,Ghosh, Prasenjit,Fagan, Paul J.,Hauptman, Elisabeth,Morris Bullock. "Metal-catalyzed selective deoxygenation of diols to alcohols". . p. 3887 - 3890. Retrieved 2007/10/03.