102152-36-3

Upstream product

• 1694-31-1 tert-butyl acetoacetate 
• 75-03-6 ethyl iodide 
• 80-58-0 2-Bromobutyric acid 
• 115-11-7 isobutene 
• 26074-52-2 2-bromo-butyryl bromide 
• 75-65-0 tert-butyl alcohol 
• 540-88-5 acetic acid tert-butyl ester 

Downstream Products

• 102152-45-4 (E)-(S)-2-Ethyl-4-(3-methyl-3H-imidazol-4-yl)-3-((S)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionyloxymethyl)-but-3-enoic acid tert-butyl ester 
• 102152-45-4 (E)-(S)-2-Ethyl-4-(3-methyl-3H-imidazol-4-yl)-3-(3,3,3-trifluoro-2-methoxy-2-phenyl-propionyloxymethyl)-but-3-enoic acid tert-butyl ester 

Relevant academic research and scientific papers

Multiple Absolute Stereocontrol in Cascade Lactone Formation via Dynamic Kinetic Resolution Driven by the Asymmetric Transfer Hydrogenation of Keto Acids with Oxo-Tethered Ruthenium Catalysts

A straightforward asymmetric construction of chiral fused γ- and δ-lactones containing multiple contiguous stereocenters was successfully developed by either (1) the dynamic kinetic resolution-asymmetric transfer hydrogenation (DKR-ATH) reaction using oxo

Cephalosporin compounds

Cephalosporin compounds represented by the general formula STR1 wherein R represents a group shown by formula STR2 wherein R1 represents a hydrogen atom or a lower alkyl group of 1-3 carbon atoms and R2 represents a hydrogen atom, a lower alkyl group of 1-3 carbon atoms, a phenyl group which may be substituted by an amino or hydroxy group, a cyano group, a carboxy group, or a carboxymethyl group; said R1 and R2 may form a cycloalkylidene group of 4-6 carbon atoms together with the carbon atom to which they are bonded) or a group shown by formula --CH2 --R3 (wherein R3 represents a hydrogen atom, a halogenomethyl group, a carbamoyl group, a carboxymethyl group, α4-carboxy-3-hydroxyisothiazol-5-yl-thiomethyl group, or α2-carboxyphenylthiomethyl group); R' represents a group shown by formula STR3 (wherein Ra represents a carboxy group, a cyano group, or a carbamoyl group which may be substituted by a lower alkyl group of 1-3 carbon atoms and Rb represents a hydrogen atom or an amino group) or a group shown by formula STR4 (wherein Ra and Rb have the same significance as above); and the waveline ? shows an anti-form or syn-form bond and the salts thereof. They possess excellent antibacterial activities against gram positive bacteria and gram negative bacteria, in particular, pseudomonas aeruginosa and are useful as anti-bacterial agents.