1021541-67-2Relevant academic research and scientific papers
Palladium-catalyzed carbene insertion and trapping with carbon nucleophiles
Devine, Sean K. J.,Van Vranken, David L.
supporting information; experimental part, p. 1909 - 1911 (2009/04/18)
Palladium catalysts are shown to catalyze the three-component coupling of vinyl halides, trimethylsilyldiazomethane. and stabilized carbon nucleophiles. The reaction is believed to proceed through a palladium-carbene intermediate LX(R)Pd=CHSiMe3 that undergoes migration of the vinyl substituent to the electrophilic carbene center to generate an ν3-allylpalladium intermediate. The allylpalladium intermediate is attacked by the carbon nucleophile to generate a vinylsilane product.
