10218-83-4

Upstream product

• 593-51-1 methylamine hydrochloride 
• 7726-95-6 bromine 
• 74-89-5 methylamine 

Downstream Products

• 100477-84-7 2,6-Dibrom-3-nitro-methylammonium-phenolat 
• 1669-36-9 4-bromo-4-methyl-2,6-di-tert-butylcyclohexa-2,5-dienone 
• 100477-81-4 2,6-Dibrom-methylammonium-phenolat 
• 100477-85-8 2,6-Dibromo-3-methyl-phenol; compound with methylamine 
• 100477-83-6 2,6-Dibromo-3-chloro-phenol; compound with methylamine 

Relevant academic research and scientific papers

Nitration of primary aminofurazans with aqueous nitric acid

A convenient procedure for the synthesis of N-nitroaminofurazans by nitration of primary 3-amino-4-R-furazans (R = Me, NO2, phenyl-, methyl-NNO-azoxy-, tert-butyl-NNO-azoxy-, tert-butyldiazenyl-, etc.) with 66-77% aqueous nitric acid was develo

Ortho-Specific Bromination of Phenols

Phenol as well as 3-substituted phenols are brominated exclusively in the ortho positions by N.N-dibromomethylamine, yielding 2.6-dibrominated phenols in excellent yields.Phenols bearing an ortho-substituent need N-bromomethylamine as the brominating agent to take up one bromine atom into the free ortho-position. para-Bromination is not observed in either case. 1-Naphthol gives 2-bromo-1-naphthol, 8-hydroxyquinoline gives 7-bromo-8-hydroxyquinoline with 80percent and 98percent yield respectively. ortho-Specific chlorination of phenols was carried out in some cases using N-chloro-alkylamines.