102183-91-5

Basic information

• Product Name: 4-(4-nitrophenyl)-N-phenyl-1,3-thiazol-2-amine
• Synonyms: 4-(4-nitrophenyl)-N-phenyl-1,3-thiazol-2-amine
• CAS NO: 102183-91-5
• Molecular Weight: 297.337
• Mol File: 102183-91-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 4-(4-nitrophenyl)-N-phenyl-1,3-thiazol-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-nitrophenyl)-N-phenyl-1,3-thiazol-2-amine(102183-91-5)
• EPA Substance Registry System: 4-(4-nitrophenyl)-N-phenyl-1,3-thiazol-2-amine(102183-91-5)

Safety Data

• Hazardous Substances Data: 102183-91-5(Hazardous Substances Data)

Upstream product

• 56177-37-8 1-(4-nitrophenyl)-2-(p-tolylsulfonyloxy)ethanone 
• 103-85-5 monophenylthiourea 
• 34006-49-0 2-chloro-1-(4-nitrophenyl)ethanone 
• 99-81-0 4-Nitrophenacyl bromide 
• 102183-93-7 2-imino-4-(4-nitrophenyl)-3-phenyl-2,3-dihydrothiazole 

Downstream Products

• 110960-43-5 4-(4-nitrophenyl)-2-(N-phenyl)trifluoroacetamidothiazole 

Relevant articles and documents

Sodium fluoride as an efficient catalyst for the synthesis of 2,4-disubstituted-1,3-thiazoles and selenazoles at ambient temperature

Sodium fluoride was found to be a simple, mild and efficient catalyst for the synthesis of 2,4-disubstituted 1,3-thiazoles and selenazoles utilizing phenacyl bromides/3-(2-bromoacetyl)-2H-chromen-2-one and thiourea/ phenylthiourea/selenourea in aqueous methanol at ambient temperature. Analytically pure products are formed within 1-3 min in excellent yields.

Green approach: An efficient synthesis of 2,4-disubstituted-1,3-thiazoles and selenazoles in aqueous medium under ultrasonic irradiation

An efficient and rapid procedure for the synthesis of 2,4-disubstituted-1,3-thiazoles and selenazoles has been described by the reaction of α-bromoketones with thiourea, phenylthiourea and selenourea at ambient temperature in aqueous medium under ultrasonic irradiation. Analytically pure products were formed within 10-60 s in excellent yields. The advantageous features of this non-conventional methodology over conventional methods are the operational simplicity, easy handling, yield-enhancing, time-reducing, mild reaction conditions and no by-product production.

Lipase and deep eutectic mixture catalyzed efficient synthesis of thiazoles in water at room temperature

Lipase bio-catalyst or ammonium based deep eutectic mixture efficiently catalyzed aqueous phase synthesis of methyl-thiazole and amino-thiazole derivatives. The simple ammonium deep eutectic catalyst, easily synthesized from choline chloride and urea, is inexpensive, recyclable and bio-degradable, making it suitable for industrial applications. Springer Science+Business Media, LLC 2012.