1021880-48-7

Basic information

• Product Name: C₁₂H₂₂N₄O₆
• Synonyms: C₁₂H₂₂N₄O₆
• CAS NO: 1021880-48-7
• Molecular Weight: 318.33
• Mol File: 1021880-48-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₂H₂₂N₄O₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₂₂N₄O₆(1021880-48-7)
• EPA Substance Registry System: C₁₂H₂₂N₄O₆(1021880-48-7)

Safety Data

• Hazardous Substances Data: 1021880-48-7(Hazardous Substances Data)

Upstream product

• 6338-55-2 2-(2-(2-aminoethoxy)ethoxy)ethan-1-ol 
• 13551-86-5 α-(chloromethyl)-2-nitro-1H-imidazole-1-ethanol 

Relevant articles and documents

Hypoxia-selective, weakly basic 2-nitroimidazole delivery agents and methods of use thereof

The invention features a class of 2-nitroimidazole compounds with a secondary basic nitrogen atom and a linker bearing one or more therapeutic agents, cytotoxic agents, detectable labels, or chelating groups. In particular, the invention provides 2-nitroimidazole compounds containing a cluster of boron atoms for use in boron neutron capture therapy (BNCT). The 2-nitroimidazole compounds can be used to treat hypoxic conditions, including, e.g., cancer, inflammation, and ischemia. The weakly basic 2-nitroimidazole compounds target to hypoxic tissue and provide increased tissue concentration overall.