1021950-90-2Relevant academic research and scientific papers
Rapid synthesis of 3-aminoimidazo[1,2-a]pyridines and pyrazines
Shaabani, Ahmad,Soleimani, Ebrahim,Maleki, Ali,Moghimi-Rad, Jafar
, p. 1090 - 1095 (2008)
p-Toluenesulfonic acid catalyzed the one-pot, three-component synthesis of 3-aminoimidazo[1,2-a]pyridines and pyrazines through a condensation reaction of a 2-aminoazine, an aldehyde, and an isocyanide at room temperature. This methodology affords a number of 3-aminoimidazo[1,2-a]pyridines in reasonable yields and short reaction times without any significant optimization of the reaction conditions. Copyright Taylor & Francis Group, LLC.
