1022154-90-0

Upstream product

• 173974-88-4 1-(4-bromophenyl)-2,2-difluoroethan-1-one 
• 73183-34-3 bis(pinacol)diborane 
• 1073353-58-8 N-methoxy-N-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide 
• 65864-64-4 trimethyl(difluoromethyl)silane 

Downstream Products

• 1022154-89-7 2,2-difluoro-1-[4-(5-fluoropyridin-2-yl)phenyl]ethanone 

Relevant academic research and scientific papers

Direct and Chemoselective Synthesis of Tertiary Difluoroketones via Weinreb Amide Homologation with a CHF2-Carbene Equivalent

The homologation of Weinreb amides into difluoromethylketones with a formal nucleophilic CHF2 transfer agent is reported. Activating TMSCHF2 with potassium tert-amylate enables a convenient access to the difluorinated homologation re

Substituted inmidazoles as bombesin receptor subtype-3 modulators

Certain novel substituted imidazoles are ligands of the human bombesin receptor and, in particular, are selective ligands of the human bombesin receptor subtype-3 (BRS-3). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of BRS-3, such as obesity, and diabetes.