1073353-58-8

Basic information

• Product Name: N-Methoxy-N-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide
• Synonyms: 4-(N-Methoxy-N-methylcarbamoyl)phenylboronic acid pinacol ester;N-Methoxy-N-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide;1-(N-METHOXY-N-METHYLCARBAMOYL)-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZENE;4-(N,O-DIMETHYLHYDROXYLAMINOCARBONYL)PHENYLBORONIC ACID, PINACOL ESTER;N-Methoxy-N-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide
• CAS NO: 1073353-58-8
• Molecular Formula: C₁₅H₂₂BNO₄
• Molecular Weight: 291.15048
• Mol File: 1073353-58-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 94-101 °C
• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-Methoxy-N-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Methoxy-N-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide(1073353-58-8)
• EPA Substance Registry System: N-Methoxy-N-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide(1073353-58-8)

Safety Data

• Hazardous Substances Data: 1073353-58-8(Hazardous Substances Data)

Usage

Uses

4-(N,O-Dimethylhydroxylaminocarbonyl)phenylboronic acid, pinacol ester

Upstream product

• 586-75-4 4-chlorobenzoyl chloride 
• 73183-34-3 bis(pinacol)diborane 
• 192436-83-2 4-bromo-N-methoxy-N-methylbenzamide 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 180516-87-4 4-carboxyphenylboronic acid pinacol ester 

Downstream Products

• 1357142-85-8 [4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl](1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-benzimidazol-2-yl)methanone 
• 1022154-90-0 2,2-difluoro-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethanone 
• 1357143-04-4 ethyl 3-{-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl}-3-(1-[{2-(trimethylsilyl)ethoxy}methyl]-1H-benzo[d]imidazol-2-yl)acrylate 

Relevant articles and documents

Design, synthesis, and biological evaluation of aryl N-methoxyamide derivatives as GPR119 agonists

A series of N-methoxyamide derivatives was identified and evaluated as GPR119 agonists. Several N-methoxyamides with thienopyrimidine and pyridine scaffolds showed potent GPR119 agonistic activities. Among them, compound 9c displayed good in vitro activity and potency. Moreover, compound 9c lowered glucose excursion in mice in an oral glucose tolerance test and increased GLP-1 secretion in intestinal cells.