10222-47-6Relevant articles and documents
Palladium(II)-mediated nucleophilic cyanation of 4-substituted quinoline 1-oxide in tue presence of trimethylsilyl cyanide and an oxidant
Tagawa, Yoshinobu,Higuchi, Yoshitaka,Yamagata, Kenji,Shibata, Kazuhiko,Teshima, Daisuke
, p. 2859 - 2862 (2004)
Reaction of 4-substituted (electron-releasing group) quinoline 1-oxides (1) with trimethylsilyl cyanide in the presence of palladium(II) acetate and DDQ gave 2-cyano-4-substituted quinoline 1-oxides (2) in THF in moderate yields. It was reasoned that this