102233-68-1

Basic information

• Product Name: 2-Butenoic acid, 3-[[2-(3-thienyl)ethyl]amino]-, methyl ester
• Synonyms: 2-Butenoic acid,3-[[2-(3-thienyl)ethyl]amino]-,methyl ester;methyl 3-crotonate;
• CAS NO: 102233-68-1
• Molecular Formula: C11H15NO2S
• Molecular Weight: 225.312
• Mol File: 102233-68-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Butenoic acid, 3-[[2-(3-thienyl)ethyl]amino]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butenoic acid, 3-[[2-(3-thienyl)ethyl]amino]-, methyl ester(102233-68-1)
• EPA Substance Registry System: 2-Butenoic acid, 3-[[2-(3-thienyl)ethyl]amino]-, methyl ester(102233-68-1)

Safety Data

• Hazardous Substances Data: 102233-68-1(Hazardous Substances Data)

Upstream product

• 59311-67-0 2-(3-thienyl)ethylamine 
• 105-45-3 acetoacetic acid methyl ester 

Relevant articles and documents

Iminium Ion Mediated Cyclizations of 4-Aryl-1,4-dihydropyridines. Bridging from Nitrogen with Thiophene and an Olefin

Novel 4-aryl-1,4-dihydropyridines, possessing 2-(3-thienyl)ethyl and 1-buten-4-yl nitrogen substitution, have been prepared by a titanium-promoted Hantzsch-type condensation.Treatment of these dihydropyridines with titanium tetrachloride catalyzes generation of the dihydropyridine/iminium ion.Subsequent trapping of this ion by either the thienyl or the olefinic moiety affords cyclic products derived respectively from elimination or addition pathways available to the intermediate cation.The stereochemistry of these cyclizations is discussed, and the scope of the process is evaluated in light of N-substituted dihydropyridines that do not cyclize